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Bernard Combe Selected Research

TNFR-Fc fusion protein (etanercept)

1/2015Etanercept tapering in rheumatoid arthritis.
11/2014Sustained remission with etanercept tapering in early rheumatoid arthritis.
10/2014Repair of radiographic hip joint in juvenile rheumatoid arthritis patients treated with etanercept plus methotrexate.
7/2014Retention rates of adalimumab, etanercept and infliximab as first and second-line biotherapy in patients with rheumatoid arthritis in daily practice.
3/2014EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update.
1/2014Evaluation of the nonsteroidal anti-inflammatory drug-sparing effect of etanercept in axial spondyloarthritis: results of the multicenter, randomized, double-blind, placebo-controlled SPARSE study.
6/2013Etanercept normalises left ventricular mass in patients with rheumatoid arthritis.
9/2012Continuous efficacy of etanercept in severe and advanced ankylosing spondylitis: results from a 12-week open-label extension of the SPINE study.
8/2012Etanercept concentration in patients with rheumatoid arthritis and its potential influence on treatment decisions: a pilot study.
6/2012Combination etanercept and methotrexate provides better disease control in very early (<=4 months) versus early rheumatoid arthritis (>4 months and <2 years): post hoc analyses from the COMET study.
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Bernard Combe Research Topics

Disease

70Rheumatoid Arthritis
12/2015 - 01/2004
20Arthritis (Polyarthritis)
07/2015 - 07/2003
11Pain (Aches)
12/2015 - 06/2002
10Ankylosing Spondylitis
01/2014 - 10/2006
9Inflammation
12/2015 - 07/2006
9Rheumatic Diseases (Rheumatism)
06/2015 - 08/2009
8Necrosis
01/2015 - 06/2010
4Synovitis
07/2015 - 08/2010
4Infection
07/2014 - 06/2008
4Psoriatic Arthritis
02/2014 - 10/2006
2Fatigue
09/2015 - 01/2009
2Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis)
10/2014 - 04/2013
2Herpes Zoster
05/2014 - 07/2003
2Neoplasms (Cancer)
08/2013 - 10/2011
2Joint Diseases (Joint Disease)
12/2012 - 11/2003
2Skin Neoplasms (Skin Cancer)
09/2012 - 04/2012
2Osteoarthritis
04/2011 - 08/2010
2Tuberculosis (Tuberculoses)
01/2011 - 06/2008
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
08/2010 - 07/2003
2Hemorrhage
11/2003 - 11/2003
1Obesity
12/2015
1Chronic Disease (Chronic Diseases)
03/2015
1Experimental Arthritis
08/2014
1Human Influenza (Influenza)
07/2014
1Disease Progression
12/2013
1Sarcoidosis (Schaumann Disease)
10/2013
1Sjogren's Syndrome (Sjogren Syndrome)
06/2013
1Serum Sickness
06/2013
1Latent Tuberculosis
11/2012
1Spondylarthropathies
11/2012
1Crohn Disease (Crohn's Disease)
11/2012
1Melanoma (Melanoma, Malignant)
09/2012
1Back Pain (Backache)
09/2012
1Spondylarthritis (Spinal Arthritis)
04/2011
1Lymphoma (Lymphomas)
01/2011
1Opportunistic Infections (Opportunistic Infection)
01/2011
1Legionnaires' Disease (Legionnaire's Disease)
01/2011
1Autoimmune Diseases (Autoimmune Disease)
01/2011
1Rheumatoid Nodule
12/2010
1Lupus Nephritis
12/2010
1Acute-Phase Reaction
09/2010
1Osteitis
08/2010

Drug/Important Bio-Agent (IBA)

23Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2015 - 07/2003
20Antirheumatic Agents (DMARD)IBA
01/2015 - 11/2004
20Methotrexate (Mexate)FDA LinkGeneric
12/2014 - 07/2003
18rituximab (Mabthera)FDA Link
12/2015 - 08/2010
18TNFR-Fc fusion protein (etanercept)FDA Link
01/2015 - 07/2003
10AntibodiesIBA
03/2015 - 01/2006
8CDP870FDA Link
12/2014 - 11/2008
8infliximab (Remicade)FDA Link
07/2014 - 07/2003
7ametantrone (HAQ)IBA
12/2015 - 11/2003
7tocilizumabFDA Link
09/2015 - 01/2011
6C-Reactive ProteinIBA
12/2015 - 11/2003
5adalimumab (Humira)FDA Link
07/2014 - 06/2008
4Interleukin-6 (Interleukin 6)IBA
07/2015 - 10/2012
4golimumabFDA Link
12/2014 - 04/2012
4leflunomide (Arava)FDA LinkGeneric
01/2012 - 08/2005
3SteroidsIBA
04/2015 - 10/2007
3Rheumatoid FactorIBA
08/2014 - 10/2013
3abatacept (BELATACEPT)FDA Link
03/2014 - 01/2011
3cyclic citrullinated peptideIBA
10/2013 - 01/2006
3Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
02/2012 - 06/2003
3Immunoglobulin M (IgM)IBA
12/2010 - 01/2009
2Biological Markers (Surrogate Marker)IBA
07/2015 - 04/2011
2Carbon MonoxideIBA
03/2015 - 10/2012
2OsteoprotegerinIBA
01/2015 - 04/2011
2Anti-Idiotypic AntibodiesIBA
08/2014 - 01/2014
2B-Cell Activating FactorIBA
08/2013 - 04/2013
2Lymphotoxin-alpha (Lymphotoxin)IBA
02/2011 - 01/2011
2Immunoglobulin G (IgG)IBA
01/2011 - 12/2009
2Monoclonal AntibodiesIBA
08/2009 - 06/2008
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
07/2006 - 11/2003
1A-factor (Streptomyces)IBA
07/2015
1TESIBA
06/2015
1acetyl 4-aminosalicylic acidIBA
03/2015
1OsteopontinIBA
03/2015
1Fas Ligand Protein (Fas Ligand)IBA
12/2014
1Aminocaproic Acids (EAC)FDA LinkGeneric
10/2014
1Interleukin-10 (Interleukin 10)IBA
08/2014
1Acute-Phase Proteins (Acute-Phase Protein)IBA
08/2014
1Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA
07/2014
1Influenza Vaccines (FluMist)IBA
07/2014
1NicotineFDA Link
12/2013
1Cyclophilins (Cyclophilin)IBA
08/2013
1B-Cell Maturation AntigenIBA
08/2013
1CollagenIBA
08/2013
1TNF-Related Apoptosis-Inducing LigandIBA
08/2013
1Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
04/2013
1Tuberculin (PPD)IBA
11/2012
1GoldIBA
11/2012
1Anti-Bacterial Agents (Antibiotics)IBA
11/2012
1Interleukin-1 (Interleukin 1)IBA
05/2011
1CytokinesIBA
02/2011
1HLA-DR Antigens (HLA-DR)IBA
12/2010
1HLA-DRB1 antigen (HLA DRB1)IBA
09/2010

Therapy/Procedure

2Drug Therapy (Chemotherapy)
04/2013 - 07/2007
1Aftercare (After-Treatment)
09/2015
1Retreatment
08/2014
1Biological Therapy
05/2013
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
09/2010