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Yu-Fang Cheng Selected Research

Rolipram

12/2013Chlorbipram: a novel PDE4 inhibitor with improved safety as a potential antidepressant and cognitive enhancer.
7/2012The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats.
3/2011Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats.
1/2011Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling.

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Yu-Fang Cheng Research Topics

Disease

4Memory Disorders (Memory Loss)
07/2012 - 07/2009
4Alzheimer Disease (Alzheimer's Disease)
07/2012 - 07/2009
2Vomiting
12/2013 - 01/2011
1Nausea
12/2013
1Inflammation
07/2012
1Brain Ischemia (Cerebral Ischemia)
03/2011
1Ischemia
03/2011
1Mental Disorders (Mental Disorder)
01/2010

Drug/Important Bio-Agent (IBA)

4RolipramIBA
12/2013 - 01/2011
3Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
12/2013 - 10/2010
3Amyloid (Amyloid Fibrils)IBA
07/2012 - 10/2010
2Phosphodiesterase 4 InhibitorsIBA
07/2012 - 01/2011
2C-Reactive ProteinIBA
02/2012 - 07/2009
1PeptidesIBA
07/2012
1Adrenergic Receptors (Adrenergic Receptor)IBA
01/2011
1MicroRNAs (MicroRNA)IBA
01/2011
1Cyclic AMP (AMP, Cyclic)IBA
10/2010
1Acute-Phase Proteins (Acute-Phase Protein)IBA
07/2009

Therapy/Procedure

1Oral Administration
12/2013
1Anesthesia
01/2011
1Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2010