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Tian-Lu Cheng Selected Research

9-aminocamptothecin glucuronide

12/2014PET imaging of β-glucuronidase activity by an activity-based 124I-trapping probe for the personalized glucuronide prodrug targeted therapy.

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Tian-Lu Cheng Research Topics

Disease

30Neoplasms (Cancer)
06/2015 - 05/2004
6Colorectal Neoplasms (Colorectal Cancer)
01/2009 - 07/2004
4Leukemia
04/2015 - 02/2006
4Neoplasm Metastasis (Metastasis)
01/2010 - 07/2004
3Adenocarcinoma
06/2015 - 07/2005
3Breast Neoplasms (Breast Cancer)
06/2010 - 03/2008
2Melanoma (Melanoma, Malignant)
08/2010 - 05/2004
2Infection
06/2010 - 09/2007
2Adenoma (Adenomas)
12/2006 - 07/2005
1Burkitt Lymphoma (Burkitt's Lymphoma)
06/2015
1Breast Ductal Carcinoma
06/2015
1Colonic Neoplasms (Colon Cancer)
05/2013
1Lung Neoplasms (Lung Cancer)
01/2012
1Neurogenic Inflammation
12/2009
1Anoxia (Hypoxia)
01/2009
1Rectal Neoplasms (Rectal Cancer)
12/2007
1Stomach Neoplasms (Stomach Cancer)
09/2007
1Circulating Neoplastic Cells
04/2007
1Lymphoma (Lymphomas)
12/2006
1Microsatellite Instability
02/2006
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
02/2006
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2005
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
11/2003
1Autoimmune Diseases (Autoimmune Disease)
11/2003

Drug/Important Bio-Agent (IBA)

8GlucuronidaseIBA
01/2015 - 09/2009
4AntigensIBA
12/2014 - 08/2010
3Proteins (Proteins, Gene)IBA
06/2015 - 11/2008
3Biological Markers (Surrogate Marker)IBA
05/2013 - 07/2004
3Messenger RNA (mRNA)IBA
12/2007 - 09/2005
2AntibodiesIBA
06/2015 - 05/2013
2p38 Mitogen-Activated Protein KinasesIBA
04/2015 - 09/2013
2Interleukin-18 (Interleukin 18)IBA
01/2015 - 06/2010
2CamptothecinIBA
01/2015 - 07/2012
2EnzymesIBA
01/2015 - 05/2006
2Doxorubicin (Adriamycin)FDA LinkGeneric
12/2014 - 01/2012
2gadolinium 1,4,7,10- tetraazacyclododecane- N,N',N'',N'''- tetraacetateIBA
05/2013 - 11/2012
2CytokinesIBA
11/2008 - 05/2006
24- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
05/2006 - 05/2004
1Immunoglobulin G (IgG)IBA
06/2015
1Liposomes (Liposome)IBA
06/2015
1pegylated liposomal doxorubicinIBA
06/2015
1Quinacrine (Mepacrine)IBA
04/2015
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2015
1irinotecan (Camptosar)FDA LinkGeneric
01/2015
1Carbon MonoxideIBA
01/2015
17-ethyl-10-hydroxycamptothecin beta-glucuronideIBA
01/2015
19-aminocamptothecin glucuronideIBA
12/2014
1Bispecific AntibodiesIBA
12/2014
1monomethoxypolyethylene glycol (MPEG)IBA
12/2014
1Phospholipases A2 (Phospholipase A2)IBA
08/2014
1asparaginylendopeptidase (legumain)IBA
01/2014
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
09/2013
1Caffeine (No Doz)FDA LinkGeneric
09/2013
1GadoliniumIBA
05/2013
1cetuximab (Erbitux)FDA Link
05/2013
1Fluorescein-5-isothiocyanate (FITC)IBA
02/2012
1Transcription Factors (Transcription Factor)IBA
01/2012
1caprolactoneIBA
01/2012
1Chondroitin Sulfates (Chondroitin Sulfate)IBA
01/2012
1icodextrin (Extraneal)FDA Link
05/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2011
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
05/2011
1PeptidesIBA
06/2010
1Fluorouracil (Carac)FDA LinkGeneric
06/2010
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2010
1MelanocortinsIBA
12/2009
1Capsaicin (Zostrix)FDA Link
12/2009
1Pro-Opiomelanocortin (Proopiomelanocortin)IBA
12/2009
1Phenolphthalein (Modane)IBA
09/2009
1trastuzumab (Herceptin)FDA Link
02/2009
1Lactic AcidFDA LinkGeneric
01/2009
1Molecular Probes (Molecular Probe)IBA
01/2009
1ProdrugsIBA
11/2008
1beta-Galactosidase (Lactaid)IBA
11/2007
1Urea (Carbamide)FDA LinkGeneric
09/2007
1UreaseIBA
09/2007
1STF 62247IBA
09/2007
1Carcinoembryonic AntigenIBA
04/2007
1E2F Transcription FactorsIBA
12/2006
1Histones (Histone)IBA
12/2006
11- myristoyl- 2- (12- ((5- dimethylamino- 1- naphthalenesulfonyl)amino)dodecanoyl)- sn- glycero- 3- phosphocholineIBA
05/2006
1Aniline MustardIBA
05/2006
1tetra-n-butyl ammonium salt p-hydroxyaniline mustard glucuronideIBA
05/2006
1Single-Chain AntibodiesIBA
05/2006
1beta CateninIBA
02/2006
1Transcription Factor 7-Like 2 ProteinIBA
02/2006
1N-methylsuccinimideIBA
02/2006
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
09/2005
1Complementary DNA (cDNA)IBA
07/2005
1DNA (Deoxyribonucleic Acid)IBA
07/2004

Therapy/Procedure

4Drug Therapy (Chemotherapy)
05/2011 - 01/2008
3Heterologous Transplantation (Xenotransplantation)
01/2015 - 01/2012
2Immunotherapy
08/2010 - 11/2003
1Homologous Transplantation (Allograft)
02/2009
1Intravenous Injections
02/2009
1Radiotherapy
01/2009
1Adjuvant Chemotherapy
03/2008