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Yan Chen Selected Research

triptolide

1/2015Triptolide Induces Cell Apoptosis by Targeting H3K4me3 and Downstream Effector Proteins in KM3 Multiple Myeloma Cells.
1/2012Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B.
8/2011Triptolide-induced apoptosis by inactivating nuclear factor-kappa B apoptotic pathway in multiple myeloma in vitro.
11/2010Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells.
6/2010Effects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cells.
1/2010Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro.
11/2006Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro.
10/2006[Effects of triptolide and TNF-alpha on the expression of VEGF in Raji cells and on angiogenesis in ECV304 cells].

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Yan Chen Research Topics

Disease

187Neoplasms (Cancer)
01/2016 - 04/2003
42Infection
12/2015 - 04/2003
40Inflammation
01/2016 - 08/2003
33Leukemia
07/2015 - 04/2002
31Neoplasm Metastasis (Metastasis)
12/2015 - 05/2003
25Carcinoma (Carcinomatosis)
01/2015 - 04/2004
22Fibrosis (Cirrhosis)
03/2015 - 05/2007
21Breast Neoplasms (Breast Cancer)
05/2015 - 05/2007
21Hepatocellular Carcinoma (Hepatoma)
03/2015 - 04/2003
20Lung Neoplasms (Lung Cancer)
06/2015 - 08/2003
16Anoxia (Hypoxia)
06/2015 - 11/2003
16Chronic Obstructive Pulmonary Disease (COPD)
03/2015 - 08/2004
14Body Weight (Weight, Body)
06/2015 - 01/2002
14Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/2015 - 01/2002
14Insulin Resistance
02/2015 - 12/2002
13Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2015 - 09/2007
11Stroke (Strokes)
08/2015 - 12/2006
11Emphysema
05/2015 - 08/2005
10Multiple Myeloma
09/2015 - 10/2009
10Obesity
06/2015 - 06/2008
10Parkinson Disease (Parkinson's Disease)
04/2015 - 12/2004
10Asthma (Bronchial Asthma)
02/2015 - 01/2010
9Brain Ischemia (Cerebral Ischemia)
08/2015 - 03/2010
9Ischemia
06/2015 - 01/2005
8Osteoporosis
12/2015 - 12/2009
8Hemorrhage
12/2015 - 11/2005
8Pain (Aches)
10/2015 - 01/2007
8Stomach Neoplasms (Stomach Cancer)
05/2015 - 09/2012
8Necrosis
04/2014 - 12/2005
8Adenocarcinoma
01/2013 - 08/2003
8Lymphoma (Lymphomas)
03/2007 - 08/2002
7Hyperalgesia
10/2015 - 05/2007
7Myocardial Infarction
08/2015 - 02/2010
7Diabetes Mellitus
06/2015 - 08/2004
7Heart Failure
05/2015 - 01/2008
7Cardiovascular Diseases (Cardiovascular Disease)
03/2015 - 01/2012
7Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
03/2015 - 01/2006
7Colorectal Neoplasms (Colorectal Cancer)
02/2015 - 02/2004
7Hypertension (High Blood Pressure)
05/2014 - 09/2009
6Wounds and Injuries (Trauma)
11/2015 - 01/2006
6Lung Injury
10/2015 - 11/2005
6Thrombosis (Thrombus)
08/2015 - 02/2006
6Human Influenza (Influenza)
02/2015 - 04/2003
6Melanoma (Melanoma, Malignant)
02/2014 - 06/2008
6Pancreatitis
12/2013 - 11/2005
6Poisoning
03/2010 - 04/2003
5Liver Neoplasms (Liver Cancer)
09/2015 - 10/2011
5Fatty Liver
07/2015 - 09/2013
5Pancreatic Neoplasms (Pancreatic Cancer)
02/2015 - 02/2006

Drug/Important Bio-Agent (IBA)

34Messenger RNA (mRNA)IBA
01/2016 - 08/2003
23DNA (Deoxyribonucleic Acid)IBA
01/2015 - 02/2002
22Proteins (Proteins, Gene)IBA
07/2015 - 01/2002
20Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2015 - 01/2005
17Phosphotransferases (Kinase)IBA
01/2016 - 12/2007
17Small Interfering RNA (siRNA)IBA
01/2016 - 04/2007
17CurcuminIBA
01/2015 - 01/2002
16Glucose (Dextrose)FDA LinkGeneric
02/2015 - 03/2005
15Carbon MonoxideIBA
06/2015 - 10/2002
14Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2015 - 06/2003
12MicroRNAs (MicroRNA)IBA
01/2016 - 01/2012
11Histones (Histone)IBA
10/2015 - 09/2005
11AntigensIBA
02/2013 - 06/2006
10SmokeIBA
05/2015 - 04/2009
10Biological Markers (Surrogate Marker)IBA
01/2015 - 10/2004
9deguelinIBA
02/2015 - 07/2005
9Insulin (Novolin)FDA Link
02/2015 - 12/2002
9Benzene (Benzole)IBA
10/2013 - 04/2002
8CytokinesIBA
09/2015 - 08/2004
8triptolideIBA
01/2015 - 10/2006
8Transforming Growth Factor beta (TGF-beta)IBA
01/2010 - 08/2003
7Nasopharyngeal carcinomaIBA
10/2015 - 05/2003
7Estrogens (Estrogen)FDA Link
10/2015 - 01/2013
7RNA (Ribonucleic Acid)IBA
09/2015 - 06/2006
7Immunoglobulin E (IgE)IBA
02/2015 - 12/2009
7NF-kappa B (NF-kB)IBA
01/2015 - 04/2006
7gambogic acidIBA
10/2014 - 08/2007
7Epidermal Growth Factor (EGF)IBA
01/2013 - 08/2003
6Immunoglobulins (Immunoglobulin)IBA
01/2016 - 06/2012
6Ethanol (Ethyl Alcohol)IBA
07/2015 - 07/2007
6glucuronyl glucosamine glycan sulfate (Vessel)IBA
05/2015 - 09/2009
6Sirolimus (Rapamycin)FDA Link
01/2015 - 08/2007
6resveratrolIBA
01/2015 - 07/2006
6OxygenIBA
07/2014 - 06/2008
6ArsenicIBA
04/2014 - 07/2004
6CalciumIBA
01/2014 - 07/2006
6Liposomes (Liposome)IBA
01/2014 - 06/2005
6AntibodiesIBA
12/2013 - 03/2005
6Complementary DNA (cDNA)IBA
12/2009 - 09/2002
5Transcription Factors (Transcription Factor)IBA
12/2015 - 07/2011
5Carrier Proteins (Binding Protein)IBA
12/2015 - 04/2006
5GTP-Binding Proteins (G-Protein)IBA
04/2015 - 11/2011

Therapy/Procedure

26Drug Therapy (Chemotherapy)
01/2016 - 09/2002
26Heterologous Transplantation (Xenotransplantation)
10/2015 - 12/2007
11Radiotherapy
02/2015 - 08/2009
10Chinese Traditional Medicine (Traditional Chinese Medicine)
10/2015 - 01/2007
9Transplantation (Transplant Recipients)
04/2015 - 08/2010
7Cryosurgery
03/2015 - 01/2009
6Transplants (Transplant)
03/2014 - 02/2006
5Stents
10/2015 - 02/2006
5Lasers (Laser)
05/2015 - 06/2010