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Hong-Zhuan Chen Selected Research

Desipramine (Pertofrane)

2/2013Antidepressant desipramine leads to C6 glioma cell autophagy: implication for the adjuvant therapy of cancer.
1/2011Desipramine induces apoptosis in rat glioma cells via endoplasmic reticulum stress-dependent CHOP pathway.
9/2002Caspase 3 gene expression and [Ca2+]i homeostasis underlying desipramine-induced C6 glioma cell apoptosis.

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Hong-Zhuan Chen Research Topics

Disease

16Neoplasms (Cancer)
08/2015 - 01/2006
11Alzheimer Disease (Alzheimer's Disease)
01/2015 - 07/2003
5Glaucoma
03/2014 - 02/2006
3Memory Disorders (Memory Loss)
02/2014 - 07/2003
3Glioma (Gliomas)
02/2013 - 09/2002
3Ischemia
09/2012 - 07/2005
3Brain Ischemia (Cerebral Ischemia)
09/2012 - 01/2004
2Necrosis
02/2015 - 08/2013
2Colorectal Neoplasms (Colorectal Cancer)
01/2015 - 01/2014
2Neoplasm Metastasis (Metastasis)
03/2014 - 01/2014
2Inflammation
06/2013 - 02/2011
2Asthma (Bronchial Asthma)
06/2013 - 02/2011
2Neurodegenerative Diseases (Neurodegenerative Disease)
02/2012 - 07/2005
2Sialorrhea
12/2009 - 07/2003
2Neuroblastoma
02/2007 - 12/2005
1Hyperalgesia
07/2015
1Glioblastoma (Glioblastoma Multiforme)
05/2015
1Head and Neck Neoplasms (Head and Neck Cancer)
02/2015
1Lung Diseases (Lung Disease)
01/2015
1Reperfusion Injury
03/2014
1Experimental Melanoma
03/2014
1Dementia (Dementias)
02/2014
1Adenocarcinoma
08/2013
1Hyperplasia
06/2013
1Pneumonia (Pneumonitis)
11/2012
1Acute Lung Injury
11/2012
1Spasm (Spasms)
07/2012
1Munchausen Syndrome (Munchhausen Syndrome)
05/2011
1Struma Ovarii
05/2011
1Thyrotoxicosis
05/2011
1Hypothyroidism
05/2011
1Hyperthyroidism
05/2011
1Muscle Cramp (Cramp)
12/2009

Drug/Important Bio-Agent (IBA)

5Angiogenesis InhibitorsIBA
08/2015 - 03/2010
4Paclitaxel (Taxol)FDA LinkGeneric
08/2015 - 03/2010
4Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
03/2014 - 04/2008
4glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2014 - 07/2005
3Pilocarpine (Ocusert)FDA LinkGeneric
03/2014 - 07/2003
3Scopolamine (Hyoscine)FDA Link
02/2014 - 07/2003
3AcetylcholinesteraseIBA
01/2014 - 12/2005
3Muscarinic AgonistsIBA
08/2013 - 07/2003
3Desipramine (Pertofrane)FDA LinkGeneric
02/2013 - 09/2002
3Glucose (Dextrose)FDA LinkGeneric
09/2012 - 01/2004
3Amyloid (Amyloid Fibrils)IBA
02/2012 - 11/2003
2P-GlycoproteinIBA
08/2015 - 08/2013
2docetaxel (Taxotere)FDA Link
03/2014 - 05/2013
2Caspase 3 (Caspase-3)IBA
03/2014 - 09/2002
2satropaneIBA
08/2013 - 11/2008
2OvalbuminIBA
06/2013 - 02/2011
2anisodamineIBA
07/2012 - 02/2011
2Antidepressive Agents (Antidepressants)IBA
01/2011 - 09/2009
2PeptidesIBA
03/2010 - 11/2003
2Single-Chain AntibodiesIBA
04/2009 - 03/2008
2PMS 777IBA
02/2007 - 12/2005
1Sirolimus (Rapamycin)FDA Link
07/2015
1Opioid Receptors (Opioid Receptor)IBA
07/2015
1epidermal growth factor receptor VIIIIBA
05/2015
1SaponinsIBA
01/2015
1Apolipoproteins E (ApoE)IBA
01/2015
1GlucocorticoidsIBA
01/2015
1chondroitin sulfate proteoglycan 4IBA
03/2014
1Eosine Yellowish-(YS) (Eosin)IBA
03/2014
1Hematoxylin (Haematoxylon)IBA
03/2014
1Retinaldehyde (Retinal)IBA
03/2014
1MeptazinolIBA
02/2014
1Vincristine (Oncovin)FDA LinkGeneric
01/2014
1Molecular Chaperones (Chaperone, Molecular)IBA
01/2014
1tariquidar (XR9576)IBA
08/2013
1CytokinesIBA
06/2013
1TriterpenesIBA
02/2013
1Interleukin-6 (Interleukin 6)IBA
11/2012
1Atropine (Hyoscyamine)FDA LinkGeneric
11/2012
14- diphenylacetoxy- 1,1- dimethylpiperidiniumIBA
11/2012
1Opioid Peptides (Opioid Peptide)IBA
09/2012
1Leucine-2-Alanine Enkephalin (Enkephalin, Leucine 2 Alanine)IBA
09/2012
1EnkephalinsIBA
09/2012
1PeroxiredoxinsIBA
05/2012
1Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2012
1follicular Thyroid cancerIBA
05/2011
1Octreotide (Sandostatin)FDA LinkGeneric
05/2011
1IodineIBA
05/2011
1Cisplatin (Platino)FDA LinkGeneric
02/2011
1Dichloroacetate (Dichloroacetic Acid)IBA
02/2011
1Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
01/2011
1ChromatinIBA
01/2011
1Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2011
1Proteins (Proteins, Gene)IBA
03/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2010
1rivastigmine (Exelon)FDA LinkGeneric
12/2009
1ButyrylcholinesteraseIBA
12/2009
1PMS1339IBA
11/2009
1Acetylcholine (Acetylcholine Chloride)FDA Link
09/2009
1Fluoxetine (Prozac)FDA LinkGeneric
09/2009
1Uridine Triphosphate (UTP)IBA
09/2009
1Brain-Derived Neurotrophic Factor (BDNF)IBA
09/2009

Therapy/Procedure

4Heterologous Transplantation (Xenotransplantation)
02/2015 - 02/2011
3Drug Therapy (Chemotherapy)
08/2013 - 03/2010
1Off-Label Use
05/2011
1Thyroidectomy
05/2011
1Combination Drug Therapy (Combination Chemotherapy)
02/2011