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Ching-Huang Chen Selected Research

K 76 carboxylic acid

2/2013Novel antitumor indolizino[6,7-b]indoles with multiple modes of action: DNA cross-linking and topoisomerase I and II inhibition.
7/2012Synthesis and antitumor evaluation of novel benzo[d]pyrrolo[2,1-b]thiazole derivatives.
1/2011Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents.
6/2006Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.
12/2005Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives.
6/2005Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity.
9/2004Potent antitumor N-mustard derivatives of 9-anilinoacridine, synthesis and antitumor evaluation.

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Ching-Huang Chen Research Topics

Disease

9Neoplasms (Cancer)
02/2013 - 09/2002
7Carcinoma (Carcinomatosis)
02/2013 - 09/2004
2Colonic Neoplasms (Colon Cancer)
04/2014 - 02/2013
2Adenocarcinoma
01/2011 - 06/2005
1Prostatic Neoplasms (Prostate Cancer)
04/2014
1Lung Neoplasms (Lung Cancer)
04/2014
1Leukemia
06/2006
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2005

Drug/Important Bio-Agent (IBA)

7K 76 carboxylic acidIBA
02/2013 - 09/2004
2DNA (Deoxyribonucleic Acid)IBA
12/2005 - 11/2003
2Type II DNA Topoisomerases (Topoisomerase II)IBA
12/2005 - 11/2003
1Adenocarcinoma of lungIBA
02/2013
1CytotoxinsIBA
06/2006
1Paclitaxel (Taxol)FDA LinkGeneric
06/2005
1trioctyl phosphine oxide (TOPO)IBA
11/2003
13- (9- acridinylamino)- 5- hydroxymethylaniline ethylcarbamateIBA
09/2002
1NetropsinIBA
09/2002

Therapy/Procedure

8Heterologous Transplantation (Xenotransplantation)
04/2014 - 09/2004
3Intravenous Injections
12/2005 - 09/2004