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John A Carver Selected Research

Small Heat-Shock Proteins

2/2015Small heat-shock proteins: important players in regulating cellular proteostasis.
3/2013Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils.
3/2008The effect of small molecules in modulating the chaperone activity of alphaB-crystallin against ordered and disordered protein aggregation.

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John A Carver Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
11/2015 - 01/2010
6Cataract (Cataracts)
01/2016 - 09/2002
5Proteostasis Deficiencies
11/2014 - 03/2008
5Parkinson Disease (Parkinson's Disease)
09/2014 - 07/2004
5Shock
09/2014 - 09/2007
4Amyloid Plaque
03/2013 - 07/2004
2AIDS-Related Complex (ARC)
03/2015 - 06/2014
2Infection
02/2015 - 09/2014
2Neurodegenerative Diseases (Neurodegenerative Disease)
09/2014 - 07/2004
1Dementia (Dementias)
09/2014
1Pheochromocytoma
09/2014
1Carcinoma (Carcinomatosis)
09/2014
1HIV Infections (HIV Infection)
09/2014
1Neuritis (Polyneuritis)
09/2014
1Disease Progression
08/2011
1Amyloidosis
06/2011
1Prion Diseases (Transmissible Spongiform Encephalopathies)
11/2010
1Macular Degeneration (Age-Related Maculopathy)
09/2010
1Huntington Disease (Huntington's Disease)
06/2010
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
06/2010
1Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
01/2007
1Muscular Diseases (Myopathy)
02/2005

Drug/Important Bio-Agent (IBA)

19Amyloid (Amyloid Fibrils)IBA
11/2015 - 01/2004
14Proteins (Proteins, Gene)IBA
01/2016 - 01/2004
13Crystallins (Crystallin)IBA
01/2016 - 09/2002
9Molecular Chaperones (Chaperone, Molecular)IBA
02/2015 - 07/2004
3Small Heat-Shock ProteinsIBA
02/2015 - 03/2008
3SynucleinsIBA
09/2014 - 05/2012
3alpha-SynucleinIBA
03/2010 - 07/2004
2PeptidesIBA
01/2013 - 01/2010
2Heat-Shock Proteins (Heat-Shock Protein)IBA
10/2011 - 03/2010
2Caseins (Casein)FDA Link
01/2010 - 12/2005
1RNA (Ribonucleic Acid)IBA
03/2015
1Hemin (Panhematin)FDA Link
11/2014
1Peptide FragmentsIBA
09/2014
1Staphylococcal Protein A (A, Protein)IBA
06/2014
1Gallic AcidIBA
12/2013
1Amyloid beta-PeptidesIBA
12/2013
1Methionine (L-Methionine)FDA Link
04/2012
1PhosphoserineIBA
08/2011
114-3-3 Proteins (14-3-3 Protein)IBA
08/2011
1OxygenIBA
09/2010
1polyglutamineIBA
06/2010
1Adenosine Triphosphate (ATP)IBA
03/2010
1Recombinant ProteinsIBA
11/2009
1DesminIBA
02/2005
1N-acetyltalosaminuronic acid (NAT)IBA
02/2005

Therapy/Procedure

1Therapeutics
11/2014