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Maria Domenica Cappellini Selected Research

Chelation Therapy (Therapy, Chelation)

6/2023Therapeutic perspective for children and young adults living with thalassemia and sickle cell disease.
11/2021Luspatercept for β-thalassemia: beyond red blood cell transfusions.
11/20212021 update on clinical trials in β-thalassemia.
7/2020Beta Thalassemia: New Therapeutic Options Beyond Transfusion and Iron Chelation.
1/2020A holistic approach to iron chelation therapy in transfusion-dependent thalassemia patients with serum ferritin below 500 μg/L.
12/2017Iron Overload and Chelation Therapy in Non-Transfusion Dependent Thalassemia.
12/2017Treatment of hepatitis C virus infection with direct-acting antiviral drugs is safe and effective in patients with hemoglobinopathies.
1/2015Defining serum ferritin thresholds to predict clinically relevant liver iron concentrations for guiding deferasirox therapy when MRI is unavailable in patients with non-transfusion-dependent thalassaemia.
10/2014Management of non-transfusion-dependent thalassemia: a practical guide.
2/2014Iron chelation therapy for non-transfusion-dependent thalassemia (NTDT): a status quo.
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Maria Domenica Cappellini Research Topics

Disease

55Thalassemia
01/2024 - 04/2005
46Iron Overload
07/2023 - 10/2004
37beta-Thalassemia (Cooley's Anemia)
06/2023 - 10/2004
23Anemia
01/2023 - 06/2007
16Sickle Cell Anemia (Hemoglobin S Disease)
06/2023 - 04/2005
13Gaucher Disease (Gaucher's Disease)
01/2023 - 09/2007
8Siderosis
01/2017 - 02/2002
6Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2023 - 02/2008
6Heart Diseases (Heart Disease)
01/2023 - 05/2006
6Hemoglobinopathies
05/2022 - 04/2005
5Iron-Deficiency Anemia (Anemia, Iron Deficiency)
10/2022 - 04/2015
5Fibrosis (Cirrhosis)
01/2020 - 10/2004
5Hemolytic Anemia
01/2019 - 10/2006
5Infections
12/2017 - 08/2009
5Exanthema (Rash)
01/2017 - 05/2006
5Osteoporosis
08/2016 - 08/2008
4Heart Failure
02/2023 - 10/2004
4Neoplasms (Cancer)
10/2022 - 02/2014
4Erythropoietic Protoporphyria
03/2022 - 05/2005
4Acute Intermittent Porphyria (Porphyria, Acute)
11/2016 - 07/2006
3Disease Progression
06/2022 - 10/2010
3Thrombocytopenia (Thrombopenia)
01/2021 - 08/2012
3Inborn Genetic Diseases (Disease, Hereditary)
01/2020 - 04/2015
3Liver Cirrhosis (Hepatic Cirrhosis)
01/2018 - 12/2017
3Metabolic Bone Diseases (Osteopenia)
08/2016 - 08/2008
3Porphyrias (Porphyria)
10/2010 - 08/2009
3Hemosiderosis
04/2010 - 07/2006
2Bone Diseases (Bone Disease)
01/2023 - 11/2011
2Pain (Aches)
01/2023 - 10/2022
2Fatigue
01/2023 - 01/2019
2Congenital Abnormalities (Deformity)
01/2023 - 06/2015
2COVID-19
11/2022 - 01/2020
2Inflammation (Inflammations)
11/2022 - 01/2011
2Arthralgia (Joint Pain)
10/2022 - 07/2002
2Acute Kidney Injury (Acute Renal Failure)
01/2022 - 12/2021
2Lung Diseases (Lung Disease)
01/2022 - 01/2017
2Congenital Hemolytic Anemia (Hemolytic Anemia, Congenital)
06/2021 - 01/2017
2Splenomegaly
01/2021 - 08/2012
2Iron-Refractory Iron Deficiency Anemia
12/2020 - 04/2015
2Hepatomegaly
01/2020 - 08/2012
2Hemolysis
01/2020 - 01/2007
2Malaria
06/2019 - 10/2010
2Thrombophilia
01/2018 - 11/2009
2Cardiomyopathies (Cardiomyopathy)
09/2017 - 01/2009
2Hepatitis
01/2017 - 10/2010
2Cardiotoxicity
11/2015 - 04/2009
2Refractory Anemia
11/2012 - 01/2011

Drug/Important Bio-Agent (IBA)

64IronIBA
06/2023 - 10/2004
24DeferasiroxFDA Link
01/2022 - 05/2006
23Hemoglobins (Hemoglobin)IBA
10/2022 - 02/2014
19Ferritins (Ferritin)IBA
01/2023 - 10/2004
11Heme (Haem)IBA
03/2022 - 02/2002
11EnzymesIBA
08/2020 - 02/2002
10luspaterceptIBA
01/2024 - 06/2021
9GlobinsIBA
05/2022 - 01/2018
9Transferrin (beta 2 Transferrin)IBA
03/2022 - 01/2009
9Chelating AgentsIBA
01/2017 - 05/2006
9Deferoxamine (Desferal)FDA LinkGeneric
06/2013 - 10/2004
8HepcidinsIBA
11/2022 - 09/2009
6Glucosylceramides (Glucocerebrosides)IBA
01/2023 - 11/2012
6DeferiproneIBA
06/2013 - 05/2006
5Fetal Hemoglobin (Hemoglobin F)IBA
06/2022 - 01/2012
4Proteins (Proteins, Gene)FDA Link
01/2023 - 01/2007
4Glucosylceramidase (Glucocerebrosidase)IBA
01/2023 - 11/2012
4LigandsIBA
12/2021 - 01/2019
4Insulin-Like Growth Factor I (IGF-1)IBA
08/2016 - 11/2007
3Sickle HemoglobinIBA
06/2023 - 04/2011
3Ferrochelatase (Heme Synthetase)IBA
03/2022 - 05/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 11/2011
3GlucosidasesIBA
01/2021 - 09/2014
3metal transporting protein 1 (ferroportin)IBA
12/2020 - 09/2009
3Growth Differentiation Factor 15IBA
01/2017 - 12/2011
3Somatomedins (Somatomedin)IBA
08/2016 - 11/2007
3Alanine Transaminase (SGPT)IBA
06/2013 - 07/2002
3CreatinineIBA
01/2011 - 05/2006
2imigluceraseFDA Link
01/2023 - 08/2012
2Hydroxyurea (Hydrea)FDA LinkGeneric
01/2023 - 01/2018
2Oxygen (Dioxygen)IBA
01/2023 - 01/2022
2Activin Receptors (Activin Receptor)IBA
12/2021 - 06/2021
2ferric carboxymaltoseIBA
01/2021 - 01/2020
2GlycosphingolipidsIBA
01/2020 - 12/2014
2Amino AcidsFDA Link
01/2020 - 08/2010
2Codon (Codons)IBA
04/2019 - 08/2010
2Biomarkers (Surrogate Marker)IBA
01/2018 - 01/2017
2Antiviral Agents (Antivirals)IBA
12/2017 - 10/2010
2Thyroxine (Levothyroxine)FDA LinkGeneric
01/2017 - 08/2009
25' Untranslated Regions (5' UTR)IBA
11/2016 - 10/2012
2Growth Hormone (Somatotropin)IBA
08/2016 - 08/2008
2Diphosphonates (Bisphosphonates)IBA
12/2014 - 07/2012
2Hormones (Hormone)IBA
07/2014 - 08/2009

Therapy/Procedure

34Therapeutics
01/2023 - 10/2004
17Chelation Therapy (Therapy, Chelation)
06/2023 - 05/2007
10Splenectomy
01/2023 - 10/2006
8Blood Transfusion (Blood Transfusions)
01/2023 - 05/2006
4Erythrocyte Transfusion
07/2023 - 11/2021
4Hematopoietic Stem Cell Transplantation
06/2023 - 05/2014
3Enzyme Replacement Therapy
12/2020 - 01/2011
2Transplantation
01/2019 - 08/2010
2Stem Cell Transplantation
01/2018 - 01/2017
2Drug Therapy (Chemotherapy)
01/2015 - 02/2014