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Lu Cai Selected Research

Streptozocin (Streptozotocin)

1/2021KLF15 negatively regulates cardiac fibrosis by which SDF-1β attenuates cardiac fibrosis in type 2 diabetic mice.
1/2020Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function.
1/2020Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function.
1/2019Clopidogrel Reduces Fibronectin Accumulation and Improves Diabetes-Induced Renal Fibrosis.
7/2018Repeated Whole-Body Exposure to Low-Dose Radiation Combined With Topical Application of Basic Fibroblast Growth Factor and Zinc Accelerates Wound Healing in Diabetic Rats.
7/2018Optimal LDR to Protect the Kidney From Diabetes: Whole-Body Exposure to 25 mGy X-rays Weekly for 8 Weeks Efficiently Attenuates Renal Damage in Diabetic Mice.
5/2018Protection by dimethyl fumarate against diabetic cardiomyopathy in type 1 diabetic mice likely via activation of nuclear factor erythroid-2 related factor 2.
1/2018Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis.
11/2016Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy.
7/2015Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model.
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Lu Cai Research Topics

Disease

57Inflammation (Inflammations)
02/2022 - 12/2008
49Fibrosis (Cirrhosis)
02/2022 - 12/2004
41Diabetic Cardiomyopathies
02/2022 - 01/2003
32Neoplasms (Cancer)
01/2022 - 03/2003
26Diabetic Nephropathies (Diabetic Nephropathy)
12/2021 - 02/2004
25Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2020 - 12/2009
23Obesity
02/2022 - 12/2006
22Type 2 Diabetes Mellitus (MODY)
01/2022 - 12/2008
21Insulin Resistance
01/2020 - 02/2011
19Hyperglycemia
04/2022 - 06/2002
17Hypoxia (Hypoxemia)
01/2022 - 08/2007
16Body Weight (Weight, Body)
01/2022 - 01/2003
16Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 01/2002
16Cardiomyopathies (Cardiomyopathy)
01/2020 - 01/2003
16Diabetes Complications
01/2019 - 04/2004
12Cardiomegaly (Heart Hypertrophy)
12/2020 - 04/2013
11Hypertrophy
02/2022 - 07/2010
9Cardiotoxicity
03/2021 - 01/2002
8Hypertension (High Blood Pressure)
01/2022 - 01/2009
8Breast Neoplasms (Breast Cancer)
01/2021 - 03/2013
7Diabetes Mellitus
11/2021 - 10/2005
6Ischemia
04/2022 - 01/2003
6Non-alcoholic Fatty Liver Disease
01/2022 - 01/2016
6Fatty Liver
01/2021 - 01/2015
6Myocardial Infarction
10/2019 - 01/2002
6Metabolic Syndrome (Dysmetabolic Syndrome X)
12/2018 - 12/2008
5Necrosis
06/2021 - 01/2003
5Atherosclerosis
03/2021 - 01/2003
5Wounds and Injuries (Trauma)
07/2018 - 01/2008
4Heart Diseases (Heart Disease)
01/2021 - 01/2012
4Heart Failure
07/2019 - 01/2014
4Proteinuria
01/2019 - 04/2007
4Prostatic Neoplasms (Prostate Cancer)
01/2018 - 07/2011
4Hyperlipidemias (Hyperlipidemia)
01/2016 - 02/2004
3Pulmonary Arterial Hypertension
01/2022 - 01/2020
3Myocardial Ischemia (Ischemic Heart Diseases)
03/2021 - 12/2014
3Hepatocellular Carcinoma (Hepatoma)
01/2021 - 03/2018
3Kidney Diseases (Kidney Disease)
01/2021 - 01/2015
3B-Cell Lymphoma (Lymphoma, B Cell)
12/2020 - 01/2017
3Pulmonary Fibrosis (Fibrosing Alveolitis)
10/2020 - 07/2011
3Chronic Disease (Chronic Diseases)
01/2020 - 01/2003

Drug/Important Bio-Agent (IBA)

35MetallothioneinIBA
01/2022 - 03/2003
30Streptozocin (Streptozotocin)FDA Link
01/2021 - 01/2003
29Glucose (Dextrose)FDA LinkGeneric
04/2022 - 06/2002
26AntioxidantsIBA
06/2021 - 01/2003
26ZincIBA
12/2020 - 01/2006
25Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2003
23LipidsIBA
10/2021 - 02/2004
18sulforaphaneIBA
02/2022 - 01/2012
13Insulin (Novolin)FDA Link
01/2021 - 06/2002
12fibroblast growth factor 21IBA
01/2020 - 01/2011
11CadmiumIBA
03/2022 - 10/2013
11Pharmaceutical PreparationsIBA
01/2021 - 02/2004
10CollagenIBA
02/2022 - 07/2005
10Plasminogen Activator Inhibitor 1IBA
01/2021 - 04/2007
9Messenger RNA (mRNA)IBA
01/2021 - 02/2010
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2022 - 01/2003
8Transcription Factors (Transcription Factor)IBA
01/2022 - 02/2011
8Reactive Oxygen Species (Oxygen Radicals)IBA
12/2019 - 01/2009
8Connective Tissue Growth FactorIBA
03/2017 - 02/2004
7CytokinesIBA
01/2022 - 01/2003
7p38 Mitogen-Activated Protein KinasesIBA
01/2022 - 01/2010
7Fibroblast Growth Factor 1 (FGF-1)IBA
01/2022 - 03/2007
7EnzymesIBA
01/2021 - 01/2003
7Phosphotransferases (Kinase)IBA
01/2019 - 11/2006
7Therapeutic UsesIBA
03/2015 - 01/2008
6Fibronectins (Fibronectin)IBA
02/2022 - 01/2013
6Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
02/2022 - 12/2009
6Caspase 3 (Caspase-3)IBA
06/2021 - 06/2002
6Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2021 - 01/2010
6IronIBA
12/2019 - 01/2008
6CurcuminIBA
01/2019 - 06/2014
6Angiotensin IIIBA
01/2018 - 07/2011
6Small Interfering RNA (siRNA)IBA
02/2014 - 01/2010
5Fenofibrate (CiL)FDA LinkGeneric
01/2020 - 04/2016
5Chelating AgentsIBA
12/2019 - 01/2008
5Biomarkers (Surrogate Marker)IBA
05/2019 - 11/2016
5Histones (Histone)IBA
01/2019 - 01/2014
4Atrial Natriuretic Factor (ANF)IBA
02/2022 - 04/2013
4Transforming Growth Factors (Transforming Growth Factor)IBA
12/2021 - 01/2014
4Biological ProductsIBA
01/2019 - 04/2004
4Sirtuin 1IBA
03/2018 - 12/2014
4Blood Glucose (Blood Sugar)IBA
01/2016 - 01/2014
4Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2012 - 03/2007
3Environmental Pollutants (Pollutants, Environmental)IBA
03/2022 - 03/2021
3Advanced Glycation End ProductsIBA
06/2021 - 12/2004
3MicroRNAs (MicroRNA)IBA
01/2021 - 11/2013
3Malondialdehyde (Propanedial)IBA
01/2021 - 01/2010
3MetalsIBA
01/2021 - 03/2017
3Cisplatin (Platino)FDA LinkGeneric
01/2021 - 08/2013
3Fatty Acids (Saturated Fatty Acids)IBA
01/2021 - 01/2019
3Triglycerides (Triacylglycerol)IBA
01/2021 - 01/2003
3PalmitatesIBA
01/2021 - 09/2016
3ArsenicIBA
09/2019 - 07/2013
3ResveratrolIBA
01/2019 - 10/2016
34-O-methylhonokiolIBA
01/2019 - 01/2014

Therapy/Procedure

22Therapeutics
01/2022 - 01/2009
9Drug Therapy (Chemotherapy)
03/2021 - 03/2013
8Intraperitoneal Injections
01/2020 - 01/2003
4Radiotherapy
12/2021 - 01/2014