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Hendrik Buikema Selected Research

endothelium-dependent hyperpolarization factor (EDHF)

2/2009Renal endothelial function and blood flow predict the individual susceptibility to adriamycin-induced renal damage.
11/2006Altered myogenic constriction and endothelium-derived hyperpolarizing factor-mediated relaxation in small mesenteric arteries of hypertensive subtotally nephrectomized rats.
12/2005Improvement of EDHF by chronic ACE inhibition declines rapidly after withdrawal in rats with myocardial infarction.
4/2003Coronary myogenic constriction antagonizes EDHF-mediated dilation: role of KCa channels.
3/2003Endothelial dysfunction and infarct-size relate to impaired EDHF response in rat experimental chronic heart failure.

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Hendrik Buikema Research Topics

Disease

9Proteinuria
07/2015 - 01/2005
6Cardiovascular Diseases (Cardiovascular Disease)
11/2013 - 12/2002
6Hypertension (High Blood Pressure)
06/2013 - 02/2003
6Myocardial Infarction
01/2009 - 03/2004
5Heart Failure
06/2013 - 03/2003
3Inflammation
01/2014 - 01/2009
2Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
01/2014 - 08/2013
2Nephrosis
04/2009 - 06/2008
2Coronary Artery Disease (Coronary Atherosclerosis)
06/2006 - 11/2005
2Infarction
03/2004 - 03/2003
1Lymphopenia (Lymphocytopenia)
01/2014
1Sclerosis
01/2014
1Diabetic Nephropathies (Diabetic Nephropathy)
11/2013
1Hypertrophy
06/2013
1Kidney Diseases (Kidney Disease)
06/2013
1Fibrosis (Cirrhosis)
03/2013
1Pre-Eclampsia (Preeclampsia)
01/2013
1Albuminuria
01/2012
1Chronic Kidney Failure (Chronic Renal Failure)
09/2011
1Hemorrhagic Shock
09/2009
1Shock
09/2009
1Cicatrix (Scar)
04/2009
1Nephrotic Syndrome (Syndrome, Nephrotic)
06/2008
1Neointima
02/2008
1Thrombosis (Thrombus)
02/2008
1Renal Insufficiency (Renal Failure)
11/2006
1Hypotension (Low Blood Pressure)
09/2006
1Myocardial Ischemia (Ischemic Heart Diseases)
09/2006
1Left Ventricular Dysfunction
12/2005
1Hypercholesterolemia
01/2005
1Ischemia
09/2004
1Body Weight (Weight, Body)
03/2004
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
02/2003

Drug/Important Bio-Agent (IBA)

5Angiotensin IIIBA
07/2015 - 12/2002
5endothelium-dependent hyperpolarization factor (EDHF)IBA
02/2009 - 03/2003
4salicylhydroxamic acid (SHAM)IBA
01/2014 - 03/2003
3Lisinopril (Prinivil)FDA LinkGeneric
06/2013 - 12/2005
3Hydrochlorothiazide (Esidrix)FDA LinkGeneric
01/2009 - 12/2005
3zofenoprilIBA
09/2006 - 03/2004
3Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
09/2006 - 03/2004
3quinapril (Accupril)FDA LinkGeneric
12/2005 - 09/2004
2CholesterolIBA
01/2014 - 04/2009
2Messenger RNA (mRNA)IBA
01/2014 - 01/2012
2Growth Differentiation Factor 15IBA
11/2013 - 03/2013
2Epidermal Growth Factor Receptor (EGF Receptor)IBA
06/2013 - 03/2009
2AngiotensinsIBA
01/2013 - 02/2003
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
09/2009 - 01/2009
2Doxorubicin (Adriamycin)FDA LinkGeneric
02/2009 - 06/2008
2SodiumIBA
12/2005 - 02/2003
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
12/2005 - 03/2004
1fingolimod (FTY720)FDA Link
01/2014
1SEW2871IBA
01/2014
1Blood Glucose (Blood Sugar)IBA
01/2014
1Glucose (Dextrose)FDA LinkGeneric
01/2014
1vildagliptinIBA
01/2014
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
08/2013
1CreatinineIBA
06/2013
1Phenol (Carbolic Acid)FDA Link
06/2013
1PKI 166IBA
06/2013
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
06/2013
1Biological Markers (Surrogate Marker)IBA
03/2013
1Streptozocin (Streptozotocin)FDA Link
03/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2012
14- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
01/2012
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2011
1IsofluraneFDA LinkGeneric
09/2009
1Nitrous Oxide (Laughing Gas)IBA
09/2009
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
09/2009
1Anesthetics (Anesthetic Agents)IBA
09/2009
1Insulin (Novolin)FDA Link
04/2009
1Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2009
1CaveolinsIBA
04/2009
1Growth Factor ReceptorsIBA
04/2009
1Transforming Growth Factor beta (TGF-beta)IBA
04/2009
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
02/2009
1CollagenIBA
01/2009
1rosuvastatin (Crestor)FDA Link
02/2008
1C-Reactive ProteinIBA
06/2006
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
06/2006
1Neurotransmitter Agents (Neurotransmitter)IBA
03/2006
1DiureticsIBA
12/2005
1Dietary SodiumIBA
03/2004
1Acetylcholine (Acetylcholine Chloride)FDA Link
03/2003
1ReninIBA
02/2003
1AldosteroneIBA
02/2003

Therapy/Procedure

2Cardiopulmonary Bypass (Heart-Lung Bypass)
01/2014 - 03/2013
2Ligation
12/2005 - 03/2003
1Blood Transfusion (Blood Transfusions)
03/2013
1Anesthesia
09/2009
1Stents
02/2008
1Drug-Eluting Stents
02/2008
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
06/2006
1Kidney Transplantation
01/2005
1Homologous Transplantation (Allograft)
01/2005