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Martin J Brodie Selected Research

zonisamide (Zonegran)

2/2014Prospective audits with newer antiepileptic drugs in focal epilepsy: insights into population responses?
7/2012Efficacy and tolerability of zonisamide versus controlled-release carbamazepine for newly diagnosed partial epilepsy: a phase 3, randomised, double-blind, non-inferiority trial.
4/2010A prospective audit of adjunctive zonisamide in an everyday clinical setting.
4/2006Modern antiepileptic drugs: guidelines and beyond.
2/2006Zonisamide as adjunctive therapy for refractory partial seizures.
4/2005Lack of clinically significant pharmacokinetic interactions between zonisamide and lamotrigine at steady state in patients with epilepsy.
1/2005Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.
12/2004Zonisamide clinical trials: European experience.

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Martin J Brodie Research Topics

Disease

43Seizures (Seizure)
11/2015 - 03/2002
40Epilepsy (Aura)
11/2015 - 03/2002
10Partial Epilepsies (Epilepsy, Partial)
11/2015 - 01/2004
4Dizziness (Lightheadedness)
10/2014 - 12/2004
2Juvenile Myoclonic Epilepsy
09/2015 - 01/2005
2Nausea
10/2014 - 08/2009
2Ataxia (Dyssynergia)
10/2014 - 08/2009
2Fatigue
10/2011 - 12/2004
2Generalized Epilepsy
06/2011 - 01/2005
2Learning Disorders (Learning Disability)
05/2007 - 04/2002
2Mental Retardation (Idiocy)
11/2005 - 12/2004
1Pain (Aches)
09/2015
1Obesity
09/2015
1Headache (Headaches)
10/2014
1Vomiting
10/2014
1Tremor (Tremors)
10/2014
1Congenital Abnormalities (Deformity)
12/2012
1Status Epilepticus (Complex Partial Status Epilepticus)
12/2012
1Lethargy
09/2011
1Diplopia (Double Vision)
08/2009
1Erectile Dysfunction
03/2006
1Body Weight (Weight, Body)
11/2005
1Neuralgia (Stump Neuralgia)
09/2005
1Anxiety Disorders (Anxiety Disorder)
09/2005
1Neoplasms (Cancer)
02/2005
1Absence Epilepsy (Absence Seizure)
01/2005
1Anorexia
12/2004
1Channelopathies
03/2002

Drug/Important Bio-Agent (IBA)

26Anticonvulsants (Antiepileptic Drugs)IBA
11/2015 - 04/2002
9lamotrigine (Lamictal)FDA LinkGeneric
10/2011 - 09/2002
8zonisamide (Zonegran)FDA LinkGeneric
02/2014 - 12/2004
7pregabalin (Lyrica)FDA Link
02/2014 - 01/2004
6etiracetam (levetiracetam)FDA LinkGeneric
02/2014 - 05/2003
6Carbamazepine (Tegretol)FDA LinkGeneric
07/2012 - 07/2004
5Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
10/2014 - 07/2004
5topiramate (Topamax)FDA LinkGeneric
02/2014 - 04/2002
4lacosamideFDA Link
10/2014 - 02/2011
4P-GlycoproteinIBA
07/2009 - 11/2002
3Phenobarbital (Luminal)FDA Link
12/2012 - 07/2004
2Prostaglandins B (PGB)IBA
02/2014 - 09/2005
2D 23129 (retigabine)IBA
11/2013 - 11/2012
2Proteins (Proteins, Gene)IBA
06/2013 - 07/2009
2tranilast (N 5')IBA
09/2011 - 11/2002
2rufinamideFDA Link
02/2011 - 08/2009
2Phenytoin (Dilantin)FDA LinkGeneric
09/2005 - 07/2004
2Ethosuximide (Zarontin)FDA LinkGeneric
01/2005 - 07/2004
1perampanelIBA
11/2015
1Carbon MonoxideIBA
11/2015
1AntibodiesIBA
06/2013
1AutoantibodiesIBA
06/2013
1Dichlorodiphenyldichloroethane (DDD)IBA
01/2013
1SodiumIBA
11/2011
1Lennox-Gastaut type Epileptic encephalopathyIBA
02/2011
1BIA 2-093IBA
02/2011
1Sodium Channels (Sodium Channel)IBA
02/2011
1ganaxoloneIBA
02/2011
1potassium bromideIBA
12/2010
1Biological Markers (Surrogate Marker)IBA
02/2010
1HormonesIBA
07/2007
1DNA (Deoxyribonucleic Acid)IBA
05/2005
1Pentylenetetrazole (Metrazol)IBA
07/2004
1clobazam (HR 376)IBA
07/2004
1Primidone (Sertan)FDA LinkGeneric
07/2004
1tiagabine (Gabitril)FDA Link
07/2004
1felbamate (Felbatol)FDA Link
07/2004
1gabapentin (Neurontin)FDA LinkGeneric
09/2002
1remacemideIBA
05/2002
1PlasticsIBA
03/2002
1Neurotransmitter Receptors (Neurotransmitter Receptor)IBA
03/2002

Therapy/Procedure

4Drug Therapy (Chemotherapy)
02/2011 - 11/2009
1Ambulatory Care (Outpatient Care)
10/2013
1Therapeutics
06/2012
1Polypharmacy
05/2007
1Intravenous Infusions
03/2007
1Combination Drug Therapy (Combination Chemotherapy)
02/2007