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Malcolm Boyce Selected Research

YF 476

12/2013The gastrin receptor antagonist netazepide (YF476) prevents oxyntic mucosal inflammation induced by Helicobacter pylori infection in Mongolian gerbils.
1/2013The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration while increasing iNOS expression.

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Malcolm Boyce Research Topics

Disease

2Inflammation
12/2013 - 10/2005
2Asthma (Bronchial Asthma)
01/2012 - 10/2005
1Rare Diseases (Rare Disease)
05/2015
1Neuroendocrine Tumors (Neuroendocrine Tumor)
05/2015
1Carcinoid Tumor (Carcinoid)
05/2015
1Dyspepsia (Indigestion)
05/2015
1Hyperplasia
05/2015
1Gastritis
12/2013
1Infection
12/2013
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
08/2013
1Tetanus
08/2013
1Achlorhydria (Hypochlorhydria)
01/2013
1Stomach Ulcer (Gastric Ulcer)
01/2013
1Atrophic Gastritis
01/2013
1Chronic Obstructive Pulmonary Disease (COPD)
01/2012
1Migraine Disorders (Migraine)
01/2009
1Obesity
04/2008
1Orthostatic Hypotension (Postural Hypotension)
11/2004
1Dizziness (Lightheadedness)
11/2004

Drug/Important Bio-Agent (IBA)

5GastrinsIBA
05/2015 - 01/2013
3Cholecystokinin B ReceptorIBA
05/2015 - 01/2013
2YF 476IBA
12/2013 - 01/2013
1Chromogranin AIBA
05/2015
1rabeprazole (Aciphex)FDA Link
05/2015
1Pentagastrin (Peptavlon)FDA Link
05/2015
1AntibodiesIBA
08/2013
1keyhole-limpet hemocyanin (keyhole limpet hemocyanin)IBA
08/2013
1Immunoglobulin G (IgG)IBA
08/2013
1Biological Markers (Surrogate Marker)IBA
01/2013
1GhrelinIBA
01/2013
1Omeprazole (Esomeprazole)FDA LinkGeneric
01/2013
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2013
1Diclofenac (SR 38)FDA LinkGeneric
01/2013
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2013
1HormonesIBA
01/2013
14- (2- ((6- ((2- (((2,6- dichlorophenyl)methyl)oxy)ethyl)oxy)hexyl)amino)- 1- hydroxyethyl)- 2- (hydroxymethyl)phenolIBA
01/2012
1fluticasone furoateFDA Link
01/2012
1frovatriptan (Allegro)FDA Link
01/2009
1N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamideIBA
04/2008
13- (N- (3,4- dimethoxybenzyl)- 2- (2- (3- methoxy- 4- (3- o- tolylureido)phenyl)acetylamino)acetamido)propanoic acidIBA
10/2005
1Integrin alpha4beta1 (VLA-4)IBA
10/2005
1donepezil (Aricept)FDA LinkGeneric
11/2004
1Thioridazine (Mellaril)FDA LinkGeneric
11/2004

Therapy/Procedure

1Aftercare (After-Treatment)
05/2015