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Marcel B Bally Selected Research

integrin-linked kinase

9/2015Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo Model of Cancer.
5/2011Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhibitor, QLT0267.
3/2008Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.
1/2008Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).
1/2006Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.
5/2005Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.

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Marcel B Bally Research Topics

Disease

47Neoplasms (Cancer)
09/2015 - 04/2002
15Breast Neoplasms (Breast Cancer)
09/2015 - 09/2003
7Colorectal Neoplasms (Colorectal Cancer)
02/2015 - 10/2004
5Prostatic Neoplasms (Prostate Cancer)
06/2012 - 05/2005
4Carcinoma (Carcinomatosis)
02/2013 - 01/2005
3Ovarian Neoplasms (Ovarian Cancer)
03/2014 - 02/2013
3Glioblastoma (Glioblastoma Multiforme)
01/2011 - 03/2006
3Anoxia (Hypoxia)
11/2008 - 12/2007
3Fever (Fevers)
02/2008 - 06/2004
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2015 - 11/2004
2Lung Neoplasms (Lung Cancer)
12/2014 - 03/2007
2Disease Progression
06/2014 - 05/2011
2Lymphoma (Lymphomas)
01/2013 - 11/2011
2Weight Loss (Weight Reduction)
11/2009 - 11/2006
2Melanoma (Melanoma, Malignant)
08/2002 - 07/2002
1Colonic Neoplasms (Colon Cancer)
02/2015
1Diarrhea
12/2014
1Hematologic Neoplasms (Hematological Malignancy)
01/2013
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
11/2011
1Ascites
05/2011
1Vascular Tissue Neoplasms
01/2011
1Glioma (Gliomas)
06/2009
1Body Weight (Weight, Body)
01/2007
1Fibrosarcoma
01/2007
1Necrosis
08/2006

Drug/Important Bio-Agent (IBA)

14Liposomes (Liposome)IBA
02/2013 - 08/2002
10Doxorubicin (Adriamycin)FDA LinkGeneric
02/2013 - 09/2003
8irinotecan (Camptosar)FDA LinkGeneric
02/2015 - 10/2004
6integrin-linked kinaseIBA
09/2015 - 05/2005
5Fluorouracil (Carac)FDA LinkGeneric
02/2015 - 11/2008
5HOE 33342 (Hoechst 33342)IBA
02/2015 - 11/2004
4QLT 0267IBA
09/2015 - 01/2006
4gefitinib (Iressa)FDA Link
01/2013 - 04/2004
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2008 - 02/2004
3PlatinumIBA
07/2015 - 02/2013
3Lipid AIBA
02/2015 - 03/2007
3Epidermal Growth Factor Receptor (EGF Receptor)IBA
06/2014 - 04/2004
3CytotoxinsIBA
01/2013 - 02/2004
3docetaxel (Taxotere)FDA Link
05/2011 - 06/2010
3trastuzumab (Herceptin)FDA Link
01/2011 - 04/2004
3Vincristine (Oncovin)FDA LinkGeneric
01/2011 - 01/2004
3oblimersen (G3139)IBA
11/2004 - 07/2002
3Antisense OligonucleotidesIBA
11/2004 - 08/2002
2LuciferasesIBA
09/2015 - 05/2011
2DNA (Deoxyribonucleic Acid)IBA
07/2015 - 11/2004
2Estrogens (Estrogen)FDA Link
06/2014 - 04/2004
2Topotecan (Hycamtin)FDA LinkGeneric
02/2013 - 02/2013
2Small Interfering RNA (siRNA)IBA
06/2009 - 03/2006
2Sirolimus (Rapamycin)FDA Link
12/2007 - 01/2006
2Carbon MonoxideIBA
12/2007 - 03/2007
2vinorelbine (Navelbine)FDA LinkGeneric
03/2007 - 11/2004
2ManganeseIBA
01/2007 - 11/2006
2SuspensionsIBA
11/2004 - 04/2004
2OligodeoxyribonucleotidesIBA
09/2003 - 07/2002
1Caspase 3 (Caspase-3)IBA
09/2015
1Glycogen Synthase Kinase 3IBA
09/2015
1CamptothecinIBA
12/2014
1AnthracyclinesIBA
06/2014
1Progesterone Receptors (Progesterone Receptor)IBA
06/2014
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
06/2014
1Epirubicin (Ellence)FDA LinkGeneric
06/2014
1taxaneIBA
03/2014
1arsenic trioxide (Trisenox)FDA Link
01/2013
1HormonesIBA
06/2012
1protopanaxadiolIBA
06/2012
1rituximab (Mabthera)FDA Link
11/2011
1Membrane Proteins (Integral Membrane Proteins)IBA
11/2011
1Glucose (Dextrose)FDA LinkGeneric
07/2011
1AmyloseIBA
07/2011
1everolimusFDA Link
01/2011
11,2-distearoylphosphatidylethanolamine (DSPE)IBA
06/2010
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
11/2009
1Alanine Transaminase (SGPT)IBA
11/2009
1CreatinineIBA
11/2009
1Tissue Inhibitor of Metalloproteinase-1IBA
11/2008
1Interleukin-8 (Interleukin 8)IBA
11/2008
1CholesterolIBA
02/2008
1Cisplatin (Platino)FDA LinkGeneric
02/2008
1glucuronyl glucosamine glycan sulfate (Vessel)IBA
01/2008
1Estrogen Receptor alphaIBA
12/2007
1EconazoleFDA LinkGeneric
11/2006
1Protein Kinases (Protein Kinase)IBA
03/2006
1U 0126 (UO 126)IBA
03/2006
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
03/2006
1AgarIBA
03/2006
15- iodo- 3- ((3,5- dibromo- 4- hydroxyphenyl)methylene)- 2- indolinoneIBA
03/2006
1Phosphotransferases (Kinase)IBA
01/2006
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2006
1tensins (tensin)IBA
05/2005

Therapy/Procedure

17Heterologous Transplantation (Xenotransplantation)
02/2015 - 09/2003
9Drug Therapy (Chemotherapy)
07/2015 - 04/2002
4Aftercare (After-Treatment)
09/2015 - 06/2004
2Therapeutics
05/2011 - 02/2004
2Radiotherapy
11/2008 - 08/2006
1Oral Administration
06/2012
1Caloric Restriction
07/2011
1Castration
06/2009
1Catheters
01/2007
1Induced Hyperthermia (Thermotherapy)
01/2007
1Antineoplastic Combined Chemotherapy Protocols
07/2006