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William M Armstead Selected Research

nociceptin

2/2011Nociceptin/orphanin phenylalanine glutamine (FQ) receptor and cardiovascular disease.
1/2006Differential activation of ERK, p38, and JNK MAPK by nociceptin/orphanin FQ in the potentiation of prostaglandin cerebrovasoconstriction after brain injury.
8/2005NOC/oFQ activates ERK and JNK but not p38 MAPK to impair prostaglandin cerebrovasodilation after brain injury.
10/2004NMDA and age dependent cerebral hemodynamics after traumatic brain injury.
2/2004Nociceptin/orphanin FQ alters prostaglandin cerebrovascular action following brain injury.
2/2003Newborn pig nociceptin/orphanin FQ activates protein tyrosine kinase and mitogen activated protein kinase to impair NMDA cerebrovasodilation after ischemia.
1/2003PTK, MAPK, and NOC/oFQ impair hypercapnic cerebrovasodilation after hypoxia/ischemia.
12/2002Role of Nociceptin/Orphanin FQ in the physiologic and pathologic control of the cerebral circulation.
10/2002Age-dependent NOC/oFQ contribution to impaired hypotensive cerebral hemodynamics after brain injury.
8/2002Relationship between NOC/oFQ, dynorphin, and COX-2 activation in impaired NMDA cerebrovasodilation after brain injury.

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William M Armstead Research Topics

Disease

34Brain Injuries (Brain Injury)
11/2013 - 07/2002
19Hypotension (Low Blood Pressure)
02/2013 - 11/2002
12Ischemia
02/2014 - 05/2002
11Anoxia (Hypoxia)
02/2014 - 05/2002
9Stroke (Strokes)
02/2014 - 09/2006
7Hypercapnia
01/2012 - 01/2003
6Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
01/2012 - 12/2002
3Intracranial Hypertension
09/2010 - 05/2009
2Brain Hypoxia (Cerebral Hypoxia)
02/2014 - 03/2009
2Intracranial Hemorrhages (Intracranial Hemorrhage)
11/2013 - 04/2010
2Brain Ischemia (Cerebral Ischemia)
08/2010 - 10/2005
1Hyperglycemia
03/2011
1Craniocerebral Trauma (Head Injury)
03/2011
1Cardiovascular Diseases (Cardiovascular Disease)
02/2011
1Central Nervous System Diseases (CNS Diseases)
07/2010
1Brain Neoplasms (Brain Tumor)
04/2010
1Neoplasms (Cancer)
04/2010
1Glioma (Gliomas)
04/2010
1Hyperemia
03/2009
1Brain Edema (Cerebral Edema)
09/2006
1Hemorrhage
09/2006
1Pulmonary Hypertension (Ayerza Syndrome)
07/2005

Drug/Important Bio-Agent (IBA)

12Tissue Plasminogen Activator (Alteplase)FDA Link
02/2014 - 09/2004
12Protein Kinases (Protein Kinase)IBA
02/2013 - 07/2002
11N-Methylaspartate (NMDA)IBA
11/2013 - 08/2002
11U 0126 (UO 126)IBA
07/2012 - 01/2003
10Plasminogen Activators (Plasminogen Activator)IBA
07/2012 - 05/2005
10nociceptinIBA
02/2011 - 08/2002
8Phosphotransferases (Kinase)IBA
02/2013 - 08/2003
6Endothelin-1 (Endothelin 1)IBA
02/2014 - 01/2003
6Adenosine Triphosphate (ATP)IBA
03/2012 - 07/2002
6salicylhydroxamic acid (SHAM)IBA
03/2011 - 05/2002
5p38 Mitogen-Activated Protein KinasesIBA
11/2013 - 08/2003
5Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
03/2009 - 09/2004
4ProstaglandinsIBA
07/2012 - 11/2002
4Superoxides (Superoxide)IBA
10/2004 - 08/2002
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2003 - 07/2002
3Endothelins (Endothelin)IBA
02/2014 - 03/2011
3Phenylephrine (Neo-Synephrine)FDA LinkGeneric
02/2013 - 09/2010
3Dinoprostone (PGE2)FDA Link
07/2012 - 08/2005
3Carbon MonoxideIBA
05/2012 - 08/2005
3SB 203580IBA
01/2012 - 08/2003
3JNK Mitogen-Activated Protein KinasesIBA
01/2012 - 01/2006
3CalciumIBA
01/2011 - 07/2002
33- (2- carboxypiperazin- 4- yl)propyl- 1- phosphonic acid (CPP)IBA
05/2010 - 05/2009
3AdrenomedullinIBA
05/2010 - 10/2007
3Protein Isoforms (Isoforms)IBA
01/2006 - 08/2003
3Dizocilpine Maleate (Dizocilpine)IBA
10/2004 - 05/2002
3GenisteinIBA
08/2003 - 01/2003
2ChloraloseIBA
02/2014 - 10/2005
2Glutamic Acid (Glutamate)FDA Link
07/2012 - 03/2011
2Epoprostenol (Prostacyclin)FDA LinkGeneric
07/2012 - 08/2005
2Glucagon (Glukagon)FDA Link
07/2012 - 03/2011
2anthra(1,9-cd)pyrazol-6(2H)-oneIBA
07/2012 - 01/2012
2KATP ChannelsIBA
03/2012 - 02/2011
2Isoproterenol (Isoprenaline)FDA LinkGeneric
01/2012 - 09/2008
2salvinorin AIBA
01/2012 - 01/2012
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
11/2011 - 03/2011
2PapaverineIBA
09/2010 - 11/2008
2Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2008 - 09/2004
2Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
10/2004 - 08/2002
2Angiotensin IIIBA
11/2003 - 11/2002
2GTP-Binding Proteins (G-Protein)IBA
05/2003 - 01/2003
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2013
1Dopamine (Intropin)FDA LinkGeneric
02/2013
1cyclo(Trp-Asp-Pro-Val-Leu)IBA
05/2012
1polyethylene glycol-superoxide dismutaseIBA
05/2012
1kappa Opioid Receptors (kappa Opioid Receptor)IBA
01/2012
1Insulin (Novolin)FDA Link
03/2011
1Endothelin Receptors (Endothelin Receptor)IBA
03/2011
1clazosentanIBA
03/2011
1tranilast (N 5')IBA
03/2011
1Phenylalanine (L-Phenylalanine)FDA Link
02/2011
1Glutamine (L-Glutamine)FDA Link
02/2011
1Potassium Channels (Potassium Channel)IBA
01/2011
1PeptidesIBA
07/2010
1Coomassie blueIBA
04/2010
1Contrast MediaIBA
04/2010
1Integrin alphaVbeta3IBA
03/2009
1Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric
11/2008
1Amino AcidsFDA Link
09/2006
1tebufenozide (Mimic)IBA
01/2006
1Prostaglandins F (PGF)IBA
01/2006
115-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA
01/2006
1Heat-Shock Proteins (Heat-Shock Protein)IBA
09/2005
1Serine Proteases (Serine Protease)IBA
09/2004
1ZD 7155IBA
11/2003
1imidazoleIBA
08/2003
1ButadienesIBA
08/2003
1OxygenIBA
07/2003
1Free RadicalsIBA
07/2003
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
06/2003
1Protein Kinase CIBA
05/2003
1Tyrosine (L-Tyrosine)FDA Link
02/2003
1PD 98059IBA
01/2003
1tyrphostin A23IBA
01/2003
1Dynorphins (Dynorphin)IBA
08/2002
1N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA
08/2002

Therapy/Procedure

2Thrombolytic Therapy
07/2010 - 08/2009
1Intravenous Injections
03/2011