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Iridocorneal Endothelial Syndrome Summary

Description: A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.

Also Known As: Chandler Syndrome; Chandler's Syndrome; Dystrophy Endothelial Cornea; Iris Atrophy with Corneal Edema and Glaucoma; Chandlers Syndrome Show All >>

Networked: 66 relevant articles (2 outcomes, 3 trials/studies) for this Disease

Key Drugs and Agents for Iridocorneal Endothelial Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Ice : 1 study in 15 results : IBA
  2. Collagen : 1 study in 3 results : IBA
  3. Keratins (Keratin) : 3 results : IBA
  4. 1 Fuchs' endothelial Corneal dystrophy : 3 results : IBA
  5. Vimentin : 2 results : IBA
  6. Fluorouracil (Carac) : 2 results : FDA 33 Generic
  7. Antigens : 2 results : IBA
  8. Mitomycin (Mitomycin-C) : 1 result : FDA 7 Generic
  9. Tuberculin (PPD) : 1 result : IBA
  10. Tissue Plasminogen Activator (Alteplase) : 1 result : FDA 2
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Diseases Related to Iridocorneal Endothelial Syndrome

  1. Low Vision (Subnormal Vision)
  2. Atrophy
  3. Vascular Diseases (Vascular Disease)
  4. Immune System Diseases (Immune Disorders)
  5. Glaucoma
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Key Therapies for Iridocorneal Endothelial Syndrome

Efficacy Chart >>
  1. Penetrating Keratoplasty : 1 outcome 1 study in 8 results
  2. Corneal Transplantation (Keratoplasty) : 1 outcome in 13 results
  3. Transplants (Transplant) : 9 results
  4. Trabeculectomy (Trabeculoplasty) : 7 results
  5. Descemet Stripping Endothelial Keratoplasty : 3 results
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