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Enzyme Replacement Therapy Summary

Description: Therapeutic replacement or supplementation of defective or missing enzymes to alleviate the effects of enzyme deficiency (e.g., GLUCOSYLCERAMIDASE replacement for GAUCHER DISEASE).

Also Known As: Enzyme Replacement Therapies; Replacement Therapies, Enzyme; Replacement Therapy, Enzyme; Therapies, Enzyme Replacement; Therapy, Enzyme Replacement

Networked: 1630 relevant articles (204 outcomes, 196 trials/studies) for this Therapy

Key Diseases for which Enzyme Replacement Therapy is Relevant

  1. Gaucher Disease (Gaucher's Disease) : 50 outcomes 27 studies in 385 results
  2. Fabry Disease (Fabry's Disease) : 40 outcomes 55 studies in 395 results
  3. Glycogen Storage Disease Type II (Pompe's Disease) : 33 outcomes 32 studies in 241 results
  4. Mucopolysaccharidoses : 9 outcomes 18 studies in 138 results
  5. Neuralgia (Stump Neuralgia) : 8 outcomes 5 studies in 17 results
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Drugs Related to Enzyme Replacement Therapy

  1. human GAA protein (Myozyme)
  2. Glucosylceramidase (Glucocerebrosidase)
  3. imiglucerase (Cerezyme)
  4. alglucerase (Ceredase)
  5. idursulfase
  6. agalsidase alfa
  7. agalsidase beta
  8. Glucosidases
  9. Mannose (D-Mannose)
  10. alpha-Galactosidase (Beano)
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Therapies Related to Enzyme Replacement Therapy

  1. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  2. Transplants (Transplant)
  3. Intravenous Infusions
  4. Mechanical Ventilators (Ventilator)
  5. Transplantation (Transplant Recipients)
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