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Cathepsin K Summary

Description: A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.

Key Diseases for which Cathepsin K is Relevant

  1. Osteoporosis : 5 outcomes 14 studies in 110 results
  2. Bone Resorption : 4 outcomes 19 studies in 252 results
  3. Postmenopausal Osteoporosis : 3 outcomes 4 studies in 16 results
  4. Inflammation : 2 outcomes 3 studies in 23 results
  5. Neoplasms (Cancer) : 1 outcome 5 studies in 60 results
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Drugs Related to Cathepsin K

  1. odanacatib
  2. Collagen
  3. Phosphotransferases (Kinase)
  4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  5. Chalcones
  6. Proteasome Endopeptidase Complex (Proteasome)
  7. Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)
  8. P-Glycoprotein
  9. Tubulin
  10. Oxidoreductases
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Therapies Related to Cathepsin K

  1. Rectal Administration
  2. Ligation
  3. Aftercare (After-Treatment)
  4. Drug Therapy (Chemotherapy)
  5. Tooth Movement
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