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Cryopyrin-Associated Periodic Syndromes
Summary
Description:
A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 protein mutations.
Also Known As:
Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome; Cold Urticaria, Familial; Cold Urticarias, Familial; Cryopyrin Associated Periodic Syndromes; Cryopyrin-Associated Periodic Syndrome Show All >>
Networked: 268
relevant articles (21 outcomes,
19 trials/studies)
for this Disease
Key Drugs and Agents for Cryopyrin-Associated Periodic Syndromes
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
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Interleukin-1 (Interleukin 1)
:
7 outcomes 1 study in 63 results
: IBA
-
canakinumab
:
6 outcomes 7 studies in 32 results
:
FDA 2
-
Interleukin 1 Receptor Antagonist Protein (Anakinra)
:
5 outcomes 3 studies in 50 results
:
FDA 2
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autosomal dominant familial Periodic fever
:
3 outcomes 2 studies in 53 results
: IBA
-
rilonacept
:
1 outcome 1 study in 10 results
:
FDA 2
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Interleukin-1 Receptors (Interleukin 1 Receptor)
:
1 outcome in 7 results
: IBA
-
Immunoglobulin G (IgG)
:
1 outcome in 2 results
: IBA
-
Thalidomide (Thalomid)
:
1 outcome in 1 result
:
FDA 2
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Interleukins
:
1 study in 20 results
: IBA
-
Synovitis granulomatous with uveitis and cranial neuropathies
:
1 study in 17 results
: IBA
Show All >>
Diseases Related to Cryopyrin-Associated Periodic Syndromes
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Familial Mediterranean Fever (Periodic Disease)
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Mevalonate Kinase Deficiency
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Schnitzler Syndrome
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Arthritis (Polyarthritis)
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Juvenile Rheumatoid Arthritis (Juvenile Idiopathic Arthritis)
Show All >>
Key Therapies for Cryopyrin-Associated Periodic Syndromes
Efficacy Chart >>
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Aftercare (After-Treatment)
:
1 outcome in 2 results
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Injections
:
1 outcome in 1 result
-
Kidney Transplantation
:
2 results
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Therapeutics
:
2 results
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Renal Dialysis (Hemodialysis)
:
2 results
Show All >>
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