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Histone Deacetylase Inhibitors Summary

Description: Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.

Also Known As: HDAC Inhibitors; Histone Deacetylase Inhibitor; Deacetylase Inhibitor, Histone; Deacetylase Inhibitors, Histone; Inhibitor, Histone Deacetylase Show All >>

Networked: 3210 relevant articles (223 outcomes, 577 trials/studies) for this Bio-Agent

Key Diseases for which Histone Deacetylase Inhibitors is Relevant

  1. Neoplasms (Cancer) : 95 outcomes 247 studies in 1391 results
  2. Leukemia : 8 outcomes 21 studies in 135 results
  3. Neurodegenerative Diseases (Neurodegenerative Disease) : 7 outcomes 6 studies in 49 results
  4. Breast Neoplasms (Breast Cancer) : 6 outcomes 25 studies in 152 results
  5. Colorectal Neoplasms (Colorectal Cancer) : 6 outcomes 6 studies in 39 results
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Drugs Related to Histone Deacetylase Inhibitors

  1. Histone Deacetylases (Histone Deacetylase)
  2. vorinostat (suberoylanilide hydroxamic acid)
  3. Valproic Acid (Valproate, Semisodium)
  4. DNA (Deoxyribonucleic Acid)
  5. LBH589
  6. trichostatin A (A 300)
  7. Butyrates (Butyrate)
  8. romidepsin (FK228)
  9. Proteasome Endopeptidase Complex (Proteasome)
  10. Histones (Histone)
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Therapies Related to Histone Deacetylase Inhibitors

  1. Drug Therapy (Chemotherapy)
  2. Therapeutics
  3. Heterologous Transplantation (Xenotransplantation)
  4. Radiotherapy
  5. Molecular Targeted Therapy
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