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Sirtuin 1 Summary

Description: A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.

Also Known As: Silent Mating Type Information Regulation 2 Homolog 1

Networked: 208 relevant articles (13 outcomes, 23 trials/studies) for this Bio-Agent

Key Diseases for which Sirtuin 1 is Relevant

  1. Atherosclerosis : 2 outcomes 1 study in 7 results
  2. Atrophy : 1 outcome 2 studies in 2 results
  3. Anoxia (Hypoxia) : 1 outcome 1 study in 18 results
  4. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 outcome 1 study in 5 results
  5. Huntington Disease (Huntington's Disease) : 1 outcome 1 study in 3 results
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Drugs Related to Sirtuin 1

  1. resveratrol
  2. Histone Deacetylases (Histone Deacetylase)
  3. NAD (NADH)
  4. Caspase 3 (Caspase-3)
  5. Staphylococcal Protein A (A, Protein)
  6. Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)
  7. Metformin (Glucophage)
  8. AMP-Activated Protein Kinases
  9. Transcription Factors (Transcription Factor)
  10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
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Therapies Related to Sirtuin 1

  1. Drug Therapy (Chemotherapy)

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