Search Login Register

Hexosaminidase A (Hex A) Summary

Description: A mammalian beta-hexosaminidase isoform that is a heteromeric protein comprized of both hexosaminidase alpha and hexosaminidase beta subunits. Deficiency of hexosaminidase A due to mutations in the gene encoding the hexosaminidase alpha subunit is a case of TAY-SACHS DISEASE. Deficiency of hexosaminidase A and HEXOSAMINIDASE B due to mutations in the gene encoding the hexosaminidase beta subunit is a case of SANDHOFF DISEASE.

Also Known As: Hex A; beta-N-Acetylhexosaminidase A; beta N Acetylhexosaminidase A

Networked: 234 relevant articles (4 outcomes, 16 trials/studies) for this Bio-Agent

Key Diseases for which Hexosaminidase A is Relevant

  1. Tay-Sachs Disease : 1 outcome 4 studies in 122 results
  2. Thyroid Neoplasms (Thyroid Cancer) : 1 outcome in 1 result
  3. Herpes Simplex : 1 outcome in 1 result
  4. Gingivitis : 1 outcome in 1 result
  5. GM2 Gangliosidoses (GM2 Gangliosidosis) : 3 studies in 47 results
Show All >>

Drugs Related to Hexosaminidase A

  1. beta-Mannosidase
  2. alpha-Mannosidase (LAMAN)
  3. Hexosaminidase B
  4. Hexosaminidases (Hexosaminidase)
  5. Isoenzymes
  6. Glycoside Hydrolases (Endoglycosidases)
  7. beta-N-Acetylhexosaminidases
  8. G(M2) Ganglioside (Ganglioside GM2)
  9. Glucuronidase
  10. alpha-L-Fucosidase (Fucosidase)
Show All >>

Therapies Related to Hexosaminidase A

  1. Enzyme Replacement Therapy
  2. Transplantation (Transplant Recipients)
  3. Intravenous Injections
  4. Oral Administration

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.