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Transforming Growth Factor beta1 (TGF beta 1) Summary

Description: A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.

Also Known As: TGF beta 1; TGF-beta-1; TGF-beta1 Latency-Associated Protein; TGF-beta1LAP; Transforming Growth Factor beta 1 Latency Associated Peptide Show All >>

Networked: 4733 relevant articles (143 outcomes, 691 trials/studies) for this Bio-Agent

Key Diseases for which Transforming Growth Factor beta1 is Relevant

  1. Fibrosis (Cirrhosis) : 32 outcomes 66 studies in 733 results
  2. Proteinuria : 13 outcomes 5 studies in 75 results
  3. Neoplasms (Cancer) : 7 outcomes 67 studies in 654 results
  4. Wounds and Injuries (Trauma) : 5 outcomes 23 studies in 204 results
  5. Inflammation : 5 outcomes 13 studies in 241 results
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Drugs Related to Transforming Growth Factor beta1

  1. Messenger RNA (mRNA)
  2. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  3. Collagen
  4. Transforming Growth Factor beta (TGF-beta)
  5. Transforming Growth Factor beta2
  6. Tissue Inhibitor of Metalloproteinase-1
  7. Fibronectins (Fibronectin)
  8. Transforming Growth Factor beta3 (TGF beta 3)
  9. Interleukin-10 (Interleukin 10)
  10. Collagen Type I (Type I Collagen)
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Therapies Related to Transforming Growth Factor beta1

  1. Transplants (Transplant)
  2. Homologous Transplantation (Allograft)
  3. Drug Therapy (Chemotherapy)
  4. Immunomodulation
  5. Oral Administration
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