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Caspase 9 Summary

Description: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

Also Known As: Apoptotic Protease Activating Factor 3; Caspase-9; ICE-LAP6 Protein; ICE-Like Apoptotic Protease 6; Pro-Caspase-9 Show All >>

Networked: 1110 relevant articles (19 outcomes, 98 trials/studies) for this Bio-Agent

Key Diseases for which Caspase 9 is Relevant

  1. Neoplasms (Cancer) : 5 outcomes 16 studies in 251 results
  2. Ischemia : 4 outcomes 5 studies in 40 results
  3. Anoxia (Hypoxia) : 1 outcome 11 studies in 70 results
  4. Breast Neoplasms (Breast Cancer) : 1 outcome 5 studies in 51 results
  5. Carcinoma (Carcinomatosis) : 1 outcome 5 studies in 35 results
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Drugs Related to Caspase 9

  1. Caspase 3 (Caspase-3)
  2. Cytochromes c (Cytochrome c)
  3. Caspase 8 (Caspase-8)
  4. Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
  5. Proteins (Proteins, Gene)
  6. Reactive Oxygen Species (Oxygen Radicals)
  7. benzyloxycarbonyl- leucyl- glutamyl- histidyl- aspartic acid fluoromethyl ketone
  8. Messenger RNA (mRNA)
  9. Glucose (Dextrose)
  10. Caspases
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Therapies Related to Caspase 9

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Diet Therapy (Therapy, Diet)
  4. Aftercare (After-Treatment)
  5. Electroacupuncture
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