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Caspase 3 (Caspase-3) Summary

Description: A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

Also Known As: Caspase-3; Procaspase-3; Apopain; Pro-Caspase-3; Pro Caspase 3; Procaspase 3; CASP3

Networked: 7145 relevant articles (193 outcomes, 629 trials/studies) for this Bio-Agent

Key Diseases for which Caspase 3 is Relevant

  1. Neoplasms (Cancer) : 35 outcomes 102 studies in 1498 results
  2. Ischemia : 12 outcomes 25 studies in 365 results
  3. Anoxia (Hypoxia) : 11 outcomes 34 studies in 443 results
  4. Inflammation : 10 outcomes 10 studies in 172 results
  5. Reperfusion Injury : 8 outcomes 8 studies in 72 results
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Drugs Related to Caspase 3

  1. Cytochromes c (Cytochrome c)
  2. Messenger RNA (mRNA)
  3. Proteins (Proteins, Gene)
  4. Caspase 9
  5. Caspase 8 (Caspase-8)
  6. Small Interfering RNA (siRNA)
  7. Annexin A5
  8. DNA (Deoxyribonucleic Acid)
  9. Calpain
  10. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
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Therapies Related to Caspase 3

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Aftercare (After-Treatment)
  4. Resuscitation
  5. Transplants (Transplant)
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