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Nitric Oxide Synthase Type II
(Inducible Nitric Oxide Synthase)
Summary
Description:
A CALCIUM-independent subtype of nitric oxide synthase that may play a role in immune function. It is an inducible enzyme whose expression is transcriptionally regulated by a variety of CYTOKINES.
Also Known As:
Inducible Nitric Oxide Synthase; INOS Enzyme; Inducible NOS Protein; NOS-II; Nitric Oxide Synthase II Show All >>
Networked: 3945
relevant articles (95 outcomes,
443 trials/studies)
for this Bio-Agent
Key Diseases for which Nitric Oxide Synthase Type II is
Relevant
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Ischemia
:
8 outcomes 26 studies in 151 results
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Inflammation
:
7 outcomes 42 studies in 505 results
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Infection
:
4 outcomes 17 studies in 308 results
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Anoxia (Hypoxia)
:
4 outcomes 16 studies in 175 results
-
Sepsis (Septicemia)
:
4 outcomes 15 studies in 111 results
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Drugs Related to Nitric Oxide Synthase Type II
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Nitric Oxide (Nitrogen Monoxide)
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Cyclooxygenase 2 (Cyclooxygenase-2)
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Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
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Messenger RNA (mRNA)
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NF-kappa B (NF-kB)
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Interleukin-1beta (Interleukin 1 beta)
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Peroxisome Proliferator-Activated Receptors (PPAR)
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Cytokines
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pimagedine (aminoguanidine)
-
3-nitrotyrosine
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Therapies Related to Nitric Oxide Synthase Type II
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Ligation
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Transplants (Transplant)
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Aftercare (After-Treatment)
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Homologous Transplantation (Allograft)
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Oral Administration
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