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Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Summary

Description: A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.

Also Known As: PACAP; PACAP-27; PACAP-38; PACAP27; PACAP38 Show All >>

Networked: 696 relevant articles (51 outcomes, 139 trials/studies) for this Bio-Agent

Key Diseases for which Pituitary Adenylate Cyclase-Activating Polypeptide is Relevant

  1. Ischemia : 12 outcomes 16 studies in 62 results
  2. Wounds and Injuries (Trauma) : 9 outcomes 3 studies in 35 results
  3. Retinal Degeneration : 6 outcomes 5 studies in 15 results
  4. Brain Ischemia (Cerebral Ischemia) : 5 outcomes 3 studies in 29 results
  5. Brain Injuries (Brain Injury) : 4 outcomes 3 studies in 22 results
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Drugs Related to Pituitary Adenylate Cyclase-Activating Polypeptide

  1. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)
  2. Retinaldehyde (Retinal)
  3. Neuropeptides
  4. Sodium Glutamate (Accent)
  5. Glutamic Acid (Glutamate)
  6. Kainic Acid (Kainate)
  7. Cisplatin (Platino)
  8. Peptides
  9. Insulin (Novolin)
  10. Substance P
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Therapies Related to Pituitary Adenylate Cyclase-Activating Polypeptide

  1. Ligation
  2. Axotomy
  3. Intensive Care (Surgical Intensive Care)
  4. Lasers (Laser)
  5. Intravenous Infusions
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