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PPAR gamma
Summary
Description:
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
Also Known As:
PPARgamma2; PPARgamma3; Peroxisome Proliferator-Activated Receptor gamma; Thiazolidinedione Receptor; mPPARgamma1 Show All >>
Networked: 3895
relevant articles (244 outcomes,
687 trials/studies)
for this Bio-Agent
Key Diseases for which PPAR gamma is
Relevant
-
Insulin Resistance
:
41 outcomes 40 studies in 458 results
-
Inflammation
:
22 outcomes 38 studies in 481 results
-
Neoplasms (Cancer)
:
18 outcomes 96 studies in 579 results
-
Atherosclerosis
:
12 outcomes 22 studies in 229 results
-
Hypertension (High Blood Pressure)
:
11 outcomes 17 studies in 117 results
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Drugs Related to PPAR gamma
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PPAR gamma
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Ligands
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Insulin (Novolin)
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rosiglitazone (Avandia)
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pioglitazone (Actos)
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Thiazolidinediones
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PPAR alpha
-
2,4-thiazolidinedione (thiazolidinedione)
-
Glucose (Dextrose)
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troglitazone (Rezulin)
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Therapies Related to PPAR gamma
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Chemoprevention
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Oral Administration
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Heterologous Transplantation (Xenotransplantation)
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Peritoneal Dialysis
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Homologous Transplantation (Allograft)
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