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Peroxisome Proliferator-Activated Receptors
(PPAR)
Summary
Description:
TRANSCRIPTION FACTORS that are activated by ligands and heterodimerize with RETINOID X RECEPTORS and bind to peroxisome proliferator response elements in the promoter regions of target genes.
Also Known As:
PPAR; NUC1 PPAR; PPAR, NUC1; Peroxisome Proliferator Activated Receptors; Proliferator-Activated Receptors, Peroxisome Show All >>
Networked: 2013
relevant articles (125 outcomes,
313 trials/studies)
for this Bio-Agent
Key Diseases for which Peroxisome Proliferator-Activated Receptors is
Relevant
-
Inflammation
:
13 outcomes 34 studies in 426 results
-
Insulin Resistance
:
11 outcomes 13 studies in 165 results
-
Fibrosis (Cirrhosis)
:
11 outcomes 8 studies in 61 results
-
Obesity
:
7 outcomes 25 studies in 161 results
-
Dyslipidemias (Dyslipidemia)
:
7 outcomes 5 studies in 78 results
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Drugs Related to Peroxisome Proliferator-Activated Receptors
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Ligands
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PPAR alpha
-
pioglitazone (Actos)
-
Insulin (Novolin)
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Fibric Acids (Fibrates)
-
Peroxisome Proliferator-Activated Receptors (PPAR)
-
PPAR gamma
-
Fenofibrate (CiL)
-
Glucose (Dextrose)
-
telmisartan (Micardis)
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Therapies Related to Peroxisome Proliferator-Activated Receptors
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Drug Therapy (Chemotherapy)
-
Therapeutics
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Laminectomy
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Ligation
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Caloric Restriction
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