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Thiazolidinediones
Summary
Description:
THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
Also Known As:
Glitazones
Networked: 1363
relevant articles (109 outcomes,
161 trials/studies)
for this Bio-Agent
Key Diseases for which Thiazolidinediones is
Relevant
-
Insulin Resistance
:
26 outcomes 24 studies in 348 results
-
Type 2 Diabetes Mellitus (MODY)
:
14 outcomes 12 studies in 192 results
-
Weight Gain
:
9 outcomes 4 studies in 91 results
-
Weight Loss (Weight Reduction)
:
8 outcomes 7 studies in 55 results
-
Inflammation
:
7 outcomes 7 studies in 52 results
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Drugs Related to Thiazolidinediones
-
Insulin (Novolin)
-
Metformin (Glucophage)
-
PPAR gamma
-
Glucose (Dextrose)
-
Fibric Acids (Fibrates)
-
Ligands
-
pioglitazone (Actos)
-
rosiglitazone (Avandia)
-
troglitazone (Rezulin)
-
Peroxisome Proliferator-Activated Receptors (PPAR)
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Therapies Related to Thiazolidinediones
-
Caloric Restriction
-
Stents
-
Phototherapy (Light Therapy)
-
Lasers (Laser)
-
Highly Active Antiretroviral Therapy (HAART)
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