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MicroRNAs (MicroRNA) Summary

Description: Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.

Also Known As: MicroRNA; miRNA; miRNAs; Micro RNA; RNA, Micro Show All >>

Networked: 18676 relevant articles (328 outcomes, 3841 trials/studies) for this Bio-Agent

Key Diseases for which MicroRNAs is Relevant

  1. Neoplasms (Cancer) : 129 outcomes 1220 studies in 8427 results
  2. Infection : 15 outcomes 165 studies in 1007 results
  3. Breast Neoplasms (Breast Cancer) : 13 outcomes 231 studies in 964 results
  4. Lung Neoplasms (Lung Cancer) : 10 outcomes 107 studies in 516 results
  5. Inflammation : 10 outcomes 81 studies in 638 results
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Drugs Related to MicroRNAs

  1. MicroRNAs (MicroRNA)
  2. Biological Markers (Surrogate Marker)
  3. Messenger RNA (mRNA)
  4. RNA (Ribonucleic Acid)
  5. Curcumin
  6. Proteins (Proteins, Gene)
  7. Histones (Histone)
  8. resveratrol
  9. Insulin (Novolin)
  10. Chromatin
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Therapies Related to MicroRNAs

  1. Therapeutics
  2. Drug Therapy (Chemotherapy)
  3. Heterologous Transplantation (Xenotransplantation)
  4. Radiotherapy
  5. Lasers (Laser)
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