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Neonatal Myasthenia Gravis (Transient Neonatal Myasthenia Gravis) Summary

Description: A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)

Also Known As: Transient Neonatal Myasthenia Gravis; Myasthenia Gravis, Neonatal; Myasthenia Gravis, Neonatal, Persistent; Myasthenia Gravis, Neonatal, Transient; Myasthenia Gravis, Persistent, Neonatal Show All >>

Networked: 32 relevant articles (0 outcomes, 1 trials/studies) for this Disease

Key Drugs and Agents for Neonatal Myasthenia Gravis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Antibodies : 13 results : IBA
  2. Acetylcholine (Acetylcholine Chloride) : 11 results : FDA 2
  3. musk : 3 results : IBA
  4. Neostigmine (Neostigmine Bromide) : 2 results : IBA
  5. Immunoglobulins (Immunoglobulin) : 2 results : IBA
  6. Immunoglobulin G (IgG) : 2 results : IBA
  7. Antigens : 2 results : IBA
  8. Blocking Antibodies : 1 result : IBA
  9. Proteins (Proteins, Gene) : 1 result : IBA
  10. Phosphotransferases (Kinase) : 1 result : IBA
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Diseases Related to Neonatal Myasthenia Gravis

  1. Myasthenia Gravis
  2. Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital)
  3. Muscle Weakness
  4. Respiratory Insufficiency (Respiratory Failure)
  5. Neuromyelitis Optica (Devic's Disease)
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Key Therapies for Neonatal Myasthenia Gravis

Efficacy Chart >>
  1. Nursing Care : 1 study in 1 result
  2. Thymectomy : 2 results
  3. Immunomodulation : 1 result
  4. Prostheses and Implants (Prosthesis) : 1 result
  5. Plasmapheresis : 1 result

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