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Lyme Neuroborreliosis Summary

Description: Nervous system infections caused by tick-borne spirochetes of the BORRELIA BURGDORFERI GROUP. The disease may affect elements of the central or peripheral nervous system in isolation or in combination. Common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), POLYRADICULOPATHY, and a mild loss of memory and other cognitive functions. Less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. In the peripheral nervous system, B. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (From J Neurol Sci 1998 Jan 8;153(2):182-91)

Also Known As: Encephalopathy, Lyme Disease; Lyme Borreliosis, Nervous System; Lyme Disease Encephalopathy; Lyme Disease Mononeuritis Multiplex; Lyme Disease, Central Nervous System Show All >>

Networked: 111 relevant articles (8 outcomes, 16 trials/studies) for this Disease

Key Drugs and Agents for Lyme Neuroborreliosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Doxycycline (Vibramycin) : 4 outcomes 4 studies in 11 results : FDA 23 Generic
  2. Ceftriaxone (Ceftriaxon) : 3 outcomes 3 studies in 10 results : FDA 33 Generic
  3. Antibodies : 2 outcomes 3 studies in 31 results : IBA
  4. Penicillin G (Benzylpenicillin) : 2 outcomes in 3 results : FDA 31 Generic
  5. Antigens : 1 outcome in 5 results : IBA
  6. Cephalosporins (Cephalosporin Antibiotics) : 1 outcome in 2 results : IBA
  7. Chemokine CXCL13 : 2 studies in 4 results : IBA
  8. Chemokines : 2 studies in 3 results : IBA
  9. Immunoglobulin M (IgM) : 1 study in 9 results : IBA
  10. Cytokines : 1 study in 6 results : IBA
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Diseases Related to Lyme Neuroborreliosis

  1. Tick-Borne Encephalitis (Encephalitis, Tick Borne)
  2. Infection
  3. Communicable Diseases (Infectious Diseases)
  4. Meningitis
  5. Paralysis (Palsy)
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Key Therapies for Lyme Neuroborreliosis

Efficacy Chart >>
  1. Aftercare (After-Treatment) : 1 study in 5 results
  2. Intravenous Infusions : 1 study in 1 result
  3. Immunotherapy : 1 study in 1 result
  4. Drug Therapy (Chemotherapy) : 2 results
  5. Hematopoietic Stem Cell Transplantation : 1 result

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