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Autonomic Dysreflexia Summary

Description: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)

Also Known As: Autonomic Dysreflexia, Spinal; Autonomic Dysreflexias; Autonomic Dysreflexias, Spinal; Autonomic Hyperreflexias; Dysreflexia, Spinal Autonomic Show All >>

Networked: 200 relevant articles (19 outcomes, 14 trials/studies) for this Disease

Key Drugs and Agents for Autonomic Dysreflexia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Nifedipine (Adalat) : 3 outcomes in 12 results : FDA 25 Generic
  2. Prazosin (Minipress) : 2 outcomes 2 studies in 3 results : FDA 24 Generic
  3. Doxazosin (Cardura) : 2 outcomes in 2 results : FDA 15 Generic
  4. Terazosin (Hytrin) : 2 outcomes in 2 results : FDA 16 Generic
  5. Lidocaine (Xylocaine) : 1 outcome 2 studies in 3 results : FDA 168 Generic
  6. Calcium Channels (Calcium Channel) : 1 outcome 1 study in 7 results : IBA
  7. Norepinephrine (Noradrenaline) : 1 outcome 1 study in 5 results : FDA 5 Generic
  8. Adrenergic Receptors (Adrenergic Receptor) : 1 outcome 1 study in 3 results : IBA
  9. Baclofen : 1 outcome in 6 results : FDA 31 Generic
  10. Capsaicin (Zostrix) : 1 outcome in 3 results : FDA 1
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Diseases Related to Autonomic Dysreflexia

  1. Spinal Cord Injuries (Spinal Cord Injury)
  2. Hypertension (High Blood Pressure)
  3. Spasm (Spasms)
  4. Shock
  5. Seizures (Seizure)
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Key Therapies for Autonomic Dysreflexia

Efficacy Chart >>
  1. Catheters : 1 outcome 1 study in 18 results
  2. Stents : 1 outcome in 9 results
  3. Lithotripsy (Extracorporeal Shockwave Lithotripsy) : 1 outcome in 8 results
  4. Epidural Analgesia : 1 outcome in 3 results
  5. Surgical Instruments (Clip) : 1 study in 6 results
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