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Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) Summary

Description: A heterogeneous group of primarily familial disorders characterized by myoclonic seizures, tonic-clonic seizures, ataxia, progressive intellectual deterioration, and neuronal degeneration. These include LAFORA DISEASE; MERRF SYNDROME; NEURONAL CEROID-LIPOFUSCINOSIS; sialidosis (see MUCOLIPIDOSES), and UNVERRICHT-LUNDBORG SYNDROME.

Also Known As: Progressive Myoclonic Epilepsy; Epilepsy, Progressive Myoclonic; Dentatorubral-Pallidoluysian Atrophy; Myoclonic Epilepsies, Progressive; Atypical Inclusion-Body Disease Show All >>

Networked: 320 relevant articles (7 outcomes, 23 trials/studies) for this Disease

Key Drugs and Agents for Progressive Myoclonic Epilepsies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cystatin B : 1 outcome 2 studies in 36 results : IBA
  2. etiracetam (levetiracetam) : 1 outcome 1 study in 7 results : FDA 45 Generic
  3. zonisamide (Zonegran) : 1 outcome 1 study in 6 results : FDA 19 Generic
  4. Serotonin (5 Hydroxytryptamine) : 1 outcome 1 study in 5 results : IBA
  5. topiramate (Topamax) : 1 outcome in 2 results : FDA 28 Generic
  6. Serotonin Agents : 1 outcome in 1 result : IBA
  7. Chloral Hydrate : 1 outcome in 1 result : IBA
  8. perampanel : 1 outcome in 1 result : IBA
  9. DNA (Deoxyribonucleic Acid) : 4 studies in 20 results : IBA
  10. Carbidopa (Lodosyn) : 3 studies in 3 results : FDA 29 Generic
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Diseases Related to Progressive Myoclonic Epilepsies

  1. Seizures (Seizure)
  2. Lafora Disease
  3. Neurodegenerative Diseases (Neurodegenerative Disease)
  4. Huntington Disease (Huntington's Disease)
  5. Spinocerebellar Ataxias (Spinocerebellar Ataxia)
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Key Therapies for Progressive Myoclonic Epilepsies

Efficacy Chart >>
  1. Vagus Nerve Stimulation : 3 results
  2. Ketogenic Diet : 2 results
  3. Deep Brain Stimulation : 2 results
  4. Lasers (Laser) : 2 results
  5. Drug Therapy (Chemotherapy) : 2 results
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