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Nocturnal Myoclonus Syndrome Summary

Description: Excessive periodic leg movements during sleep that cause micro-arousals and interfere with the maintenance of sleep. This condition induces a state of relative sleep deprivation which manifests as excessive daytime hypersomnolence. The movements are characterized by repetitive contractions of the tibialis anterior muscle, extension of the toe, and intermittent flexion of the hip, knee and ankle. (Adams et al., Principles of Neurology, 6th ed, p387)

Also Known As: Excessive Periodic Sleep-Related Leg Movements; Periodic Leg Movements, Excessive, Sleep-Related; Sleep-Related Periodic Leg Movements, Excessive; Excessive Periodic Sleep Related Leg Movements; Myoclonus Syndrome, Nocturnal Show All >>

Networked: 33 relevant articles (1 outcomes, 2 trials/studies) for this Disease

Key Drugs and Agents for Nocturnal Myoclonus Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. saccharated ferric oxide : 1 outcome in 1 result : FDA 1
  2. Clonazepam (Rivotril) : 1 study in 2 results : FDA 16 Generic
  3. Valproic Acid (Valproate, Semisodium) : 1 study in 1 result : FDA 51 Generic
  4. Dopamine Agents (Dopaminergic Agents) : 3 results : IBA
  5. Bupropion (Wellbutrin) : 2 results : FDA 28 Generic
  6. Dopamine Receptors (Dopamine Receptor) : 2 results : IBA
  7. Pergolide (Permax) : 2 results : FDA 3
  8. Iron : 2 results : IBA
  9. Dopamine (Intropin) : 2 results : FDA 36 Generic
  10. Benzodiazepines : 2 results : IBA
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Diseases Related to Nocturnal Myoclonus Syndrome

  1. Restless Legs Syndrome (Restless Legs)
  2. Sleep Initiation and Maintenance Disorders (Insomnia)
  3. Obstructive Sleep Apnea
  4. Somnambulism (Sleepwalking)
  5. REM Sleep Behavior Disorder
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Key Therapies for Nocturnal Myoclonus Syndrome

Efficacy Chart >>
  1. Cardiac Resynchronization Therapy : 1 result
  2. Off-Label Use : 1 result
  3. Deep Brain Stimulation : 1 result
  4. Continuous Positive Airway Pressure : 1 result
  5. Drug Therapy (Chemotherapy) : 1 result
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