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Cyclin-Dependent Kinase Inhibitor p16 Summary

Description: A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.

Also Known As: CDKN2 Protein; CDKN2A Protein; Cdk4-Associated Protein p16; Cyclin-Dependent Kinase Inhibitor-2A; INK4A Protein Show All >>

Networked: 1558 relevant articles (30 outcomes, 206 trials/studies) for this Bio-Agent

Key Diseases for which Cyclin-Dependent Kinase Inhibitor p16 is Relevant

  1. Neoplasms (Cancer) : 13 outcomes 69 studies in 781 results
  2. Squamous Cell Carcinoma (Epidermoid Carcinoma) : 4 outcomes 13 studies in 124 results
  3. Adenocarcinoma : 4 outcomes 10 studies in 60 results
  4. Glioblastoma (Glioblastoma Multiforme) : 2 outcomes 1 study in 16 results
  5. Lung Neoplasms (Lung Cancer) : 1 outcome 8 studies in 40 results
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Drugs Related to Cyclin-Dependent Kinase Inhibitor p16

  1. Biological Markers (Surrogate Marker)
  2. DNA (Deoxyribonucleic Acid)
  3. Messenger RNA (mRNA)
  4. Antibodies
  5. beta Catenin
  6. Carrier Proteins (Binding Protein)
  7. RNA (Ribonucleic Acid)
  8. Keratins (Keratin)
  9. trichostatin A (A 300)
  10. Acetic Acid (Vinegar)
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Therapies Related to Cyclin-Dependent Kinase Inhibitor p16

  1. Drug Therapy (Chemotherapy)
  2. Radiotherapy
  3. Aftercare (After-Treatment)
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  5. Prostatectomy (Retropubic Prostatectomy)
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