Search Login Register

Landau-Kleffner Syndrome Summary

Description: A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495)

Also Known As: Acquired Aphasia with Convulsive Disorder; Acquired Epileptiform Aphasia; Aphasia, Epileptic, Acquired; Landau-Kleffner Acquired Epileptiform Aphasia; Acquired Epileptic Aphasia Show All >>

Networked: 69 relevant articles (6 outcomes, 8 trials/studies) for this Disease

Key Drugs and Agents for Landau-Kleffner Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Immunoglobulins (Immunoglobulin) : 1 outcome 1 study in 3 results : IBA
  2. Adrenocorticotropic Hormone (ACTH) : 1 outcome 1 study in 2 results : FDA 7
  3. Lennox-Gastaut type Epileptic encephalopathy : 1 outcome in 19 results : IBA
  4. Intravenous Immunoglobulins (IVIG) : 1 outcome in 6 results : FDA 1
  5. Adrenal Cortex Hormones (Corticosteroids) : 1 outcome in 4 results : IBA
  6. Benzodiazepines : 1 outcome in 2 results : IBA
  7. Glucose (Dextrose) : 2 studies in 4 results : FDA 175 Generic
  8. Steroids : 1 study in 3 results : IBA
  9. Prednisolone (Predate) : 1 study in 1 result : FDA 55 Generic
  10. Methylprednisolone : 1 study in 1 result : FDA 18 Generic
Show All >>

Diseases Related to Landau-Kleffner Syndrome

  1. Epilepsy (Aura)
  2. Malformations of Cortical Development
  3. Tuberous Sclerosis (Bourneville's Disease)
  4. Sturge-Weber Syndrome (Sturge-Kalischer-Weber Syndrome)
  5. Infantile Spasms (West Syndrome)
Show All >>

Key Therapies for Landau-Kleffner Syndrome

Efficacy Chart >>
  1. Aftercare (After-Treatment) : 1 outcome in 1 result
  2. Sign Language : 2 studies in 5 results
  3. Ketogenic Diet : 3 results
  4. Vagus Nerve Stimulation : 1 result
  5. General Anesthesia : 1 result

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.