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Pleurodesis Summary

Description: The production of adhesions between the parietal and visceral pleura. The procedure is used in the treatment of bronchopleural fistulas, malignant pleural effusions, and pneumothorax and often involves instillation of chemicals or other agents into the pleural space causing, in effect, a pleuritis that seals the air leak. (From Fishman, Pulmonary Diseases, 2d ed, p2233 & Dorland, 27th ed)

Key Diseases for which Pleurodesis is Relevant

  1. Pneumothorax : 45 outcomes 26 studies in 358 results
  2. Malignant Pleural Effusion : 38 outcomes 56 studies in 292 results
  3. Pleural Effusion (Pleural Effusions) : 22 outcomes 15 studies in 238 results
  4. Chylothorax : 9 outcomes 2 studies in 73 results
  5. Hydrothorax : 7 outcomes 2 studies in 46 results
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Drugs Related to Pleurodesis

  1. Talc
  2. Picibanil
  3. Tetracycline (Achromycin)
  4. Doxycycline (Vibramycin)
  5. Minocycline (Cyclops)
  6. Bleomycin (Blenoxane)
  7. Fibrin Tissue Adhesive (Fibrin Sealant)
  8. Glucose (Dextrose)
  9. Povidone-Iodine (Betadine)
  10. Sclerosing Solutions (Sclerosing Agents)
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Therapies Related to Pleurodesis

  1. Catheters
  2. Thoracostomy
  3. Chest Tubes (Chest Tube)
  4. Ligation
  5. Palliative Care (Palliative Medicine)
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