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Pyoderma Gangrenosum Summary

Description: An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.

Key Drugs and Agents for Pyoderma Gangrenosum

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. infliximab (Remicade) : 13 outcomes 3 studies in 76 results : FDA 2
  2. Cyclosporine (Ciclosporin) : 13 outcomes 2 studies in 88 results : FDA 20 Generic
  3. Tacrolimus (Prograf) : 10 outcomes 3 studies in 45 results : FDA 7 Generic
  4. Prednisolone (Predate) : 7 outcomes 2 studies in 18 results : FDA 55 Generic
  5. Dapsone : 4 outcomes 2 studies in 22 results : FDA 3
  6. Adrenal Cortex Hormones (Corticosteroids) : 4 outcomes in 40 results : IBA
  7. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 3 outcomes 1 study in 26 results : IBA
  8. mycophenolate mofetil (Cellcept) : 3 outcomes in 13 results : FDA 24 Generic
  9. Intravenous Immunoglobulins (IVIG) : 3 outcomes in 8 results : FDA 1
  10. Cyclophosphamide (Cytoxan) : 2 outcomes 1 study in 7 results : FDA 10 Generic
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Diseases Related to Pyoderma Gangrenosum

  1. Psoriasis (Pustulosis Palmaris et Plantaris)
  2. Lichen Planus (Lichen Ruber Planus)
  3. Ulcerative Colitis
  4. Skin Diseases
  5. Crohn Disease (Crohn's Disease)
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Key Therapies for Pyoderma Gangrenosum

Efficacy Chart >>
  1. Blood Component Removal (Apheresis) : 3 outcomes 2 studies in 9 results
  2. Drug Therapy (Chemotherapy) : 2 outcomes in 5 results
  3. Transplants (Transplant) : 1 outcome in 15 results
  4. Colectomy : 1 outcome in 9 results
  5. Transplantation (Transplant Recipients) : 1 outcome in 6 results
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