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Kallmann Syndrome (Kallmann's Syndrome) Summary

Description: A genetically heterogeneous disorder caused by hypothalamic GNRH deficiency and OLFACTORY NERVE defects. It is characterized by congenital HYPOGONADOTROPIC HYPOGONADISM and ANOSMIA, possibly with additional midline defects. It can be transmitted as an X-linked (GENETIC DISEASES, X-LINKED), an autosomal dominant, or an autosomal recessive trait.

Also Known As: Kallmann's Syndrome; Autosomal Dominant Form of Kallmann Syndrome; Kallmann Syndrome 1; Kallmann Syndrome 2; Kallmann Syndrome, Type 1, X-linked Show All >>

Networked: 280 relevant articles (4 outcomes, 10 trials/studies) for this Disease

Key Drugs and Agents for Kallmann Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Gonadotropin-Releasing Hormone (GnRH) : 4 outcomes 4 studies in 124 results : FDA 2
  2. Gonadotropins : 1 outcome in 35 results : IBA
  3. Prolactin : 1 outcome in 2 results : IBA
  4. Dopamine Agonists (Dopamine Agonist) : 1 outcome in 1 result : IBA
  5. Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1) : 1 study in 16 results : IBA
  6. Congenital anosmia : 1 study in 11 results : IBA
  7. Luteinizing Hormone (Lutropin) : 1 study in 7 results : FDA 5 Generic
  8. Follicle Stimulating Hormone (Follitropin) : 1 study in 6 results : FDA 1
  9. Antibodies : 1 study in 2 results : IBA
  10. Insulin (Novolin) : 1 study in 1 result : FDA 2
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Diseases Related to Kallmann Syndrome

  1. Hypogonadism (Hypergonadotropic Hypogonadism)
  2. Hyperprolactinemia
  3. Starvation
  4. Pituitary Diseases (Disease, Anterior Pituitary)
  5. Diabetes Mellitus
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Key Therapies for Kallmann Syndrome

Efficacy Chart >>
  1. Infusion Pumps (Infusion Pump) : 4 results
  2. Ligation : 2 results
  3. Injections : 2 results
  4. Prostheses and Implants (Prosthesis) : 1 result
  5. Tissue Expansion Devices (Tissue Expander) : 1 result
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