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Interferon-alpha (Interferon Alfa) Summary

Description: One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.

Also Known As: Interferon Alfa; Glaxo Wellcome Brand of Interferon alfa-n1; Interferon Alfa-n1; Interferon Alfa-n3; Interferon, Lymphoblastoid Show All >>

Networked: 10282 relevant articles (1135 outcomes, 1548 trials/studies) for this Drug

Key Diseases for which Interferon-alpha is Relevant

  1. Chronic Hepatitis C : 188 outcomes 220 studies in 1644 results
  2. Infection : 149 outcomes 152 studies in 1489 results
  3. Chronic Hepatitis B : 106 outcomes 109 studies in 600 results
  4. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) : 74 outcomes 69 studies in 559 results
  5. Renal Cell Carcinoma (Grawitz Tumor) : 60 outcomes 148 studies in 528 results
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Drugs Related to Interferon-alpha

  1. Ribavirin (Virazole)
  2. Interferons
  3. Interleukin-2 (IL2)
  4. Hepatitis B e Antigens
  5. Lamivudine (3TC)
  6. Fluorouracil (Carac)
  7. RNA (Ribonucleic Acid)
  8. Interferon-alpha (Interferon Alfa)
  9. Antigens
  10. Zidovudine (Retrovir)
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Therapies Related to Interferon-alpha

  1. Drug Therapy (Chemotherapy)
  2. Aftercare (After-Treatment)
  3. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  4. Retreatment
  5. Transplants (Transplant)
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