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Eosinophilia-Myalgia Syndrome Summary

Description: A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Also Known As: Eosinophilia-Myalgia Syndrome, L-Tryptophan-Related; L-Tryptophan-Related Eosinophilia-Myalgia Syndrome; Syndrome, Eosinophilia-Myalgia, L-Tryptophan-Related; Eosinophilia Myalgia Syndrome; Eosinophilia-Myalgia Syndromes Show All >>

Networked: 298 relevant articles (3 outcomes, 19 trials/studies) for this Disease

Key Drugs and Agents for Eosinophilia-Myalgia Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Tryptophan (L-Tryptophan) : 2 outcomes 18 studies in 265 results : FDA 30
  2. Kynurenine : 1 outcome in 4 results : IBA
  3. Vitamins : 1 outcome in 1 result : IBA
  4. Prednisolone (Predate) : 1 outcome in 1 result : FDA 55 Generic
  5. 1,1'-ethylidene bis(tryptophan) : 1 study in 3 results : IBA
  6. Autoantibodies : 1 study in 2 results : IBA
  7. Eosinophil Cationic Protein : 1 study in 1 result : IBA
  8. 1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP) : 1 study in 1 result : IBA
  9. Vinyl Chloride (Chloroethylene) : 1 study in 1 result : IBA
  10. Polychlorinated Biphenyls (PCBs) : 1 study in 1 result : IBA
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Diseases Related to Eosinophilia-Myalgia Syndrome

  1. Fibrosis (Cirrhosis)
  2. Fasciitis (Fascitis)
  3. Sclerosis
  4. Poisoning
  5. Neuritis (Polyneuritis)
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Key Therapies for Eosinophilia-Myalgia Syndrome

Efficacy Chart >>
  1. Transplants (Transplant) : 1 result
  2. Nutritional Support (Artificial Feeding) : 1 result
  3. Breast Implants (Breast Implant) : 1 result
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 1 result
  5. Transplantation (Transplant Recipients) : 1 result
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