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Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) Summary

Description: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.

Also Known As: Thrombocytopenic Purpura, Autoimmune; Purpura, Thrombocytopenic, Idiopathic; Autoimmune Thrombocytopenia; Werlhof Disease; Autoimmune Thrombocytopenias Show All >>

Networked: 3202 relevant articles (178 outcomes, 236 trials/studies) for this Disease

Key Drugs and Agents for Idiopathic Thrombocytopenic Purpura

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Inosine Triphosphate (ITP) : 90 outcomes 149 studies in 1697 results : IBA
  2. Intravenous Immunoglobulins (IVIG) : 13 outcomes 13 studies in 112 results : FDA 1
  3. Immunoglobulins (Immunoglobulin) : 12 outcomes 16 studies in 198 results : IBA
  4. rituximab (Mabthera) : 11 outcomes 7 studies in 90 results : FDA 3
  5. Danazol (Azol) : 8 outcomes 1 study in 49 results : FDA 5 Generic
  6. Immunoglobulin G (IgG) : 7 outcomes 8 studies in 196 results : IBA
  7. Dexamethasone (Maxidex) : 5 outcomes 6 studies in 35 results : FDA 77 Generic
  8. eltrombopag : 5 outcomes 3 studies in 33 results : FDA 1
  9. Prednisone (Sone) : 5 outcomes 2 studies in 38 results : FDA 119 Generic
  10. Prednisolone (Predate) : 5 outcomes in 38 results : FDA 55 Generic
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Diseases Related to Idiopathic Thrombocytopenic Purpura

  1. Thrombocytopenia (Thrombopenia)
  2. Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
  3. Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
  4. Systemic Lupus Erythematosus (Libman-Sacks Disease)
  5. Hemolytic Anemia
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Key Therapies for Idiopathic Thrombocytopenic Purpura

Efficacy Chart >>
  1. Splenectomy : 30 outcomes 28 studies in 470 results
  2. Drug Therapy (Chemotherapy) : 3 outcomes 1 study in 28 results
  3. Transplants (Transplant) : 2 outcomes 2 studies in 23 results
  4. Platelet Transfusion (Blood Platelet Transfusions) : 1 outcome 3 studies in 26 results
  5. Aftercare (After-Treatment) : 1 outcome 1 study in 13 results
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