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Idiopathic Thrombocytopenic Purpura
(Thrombocytopenic Purpura, Autoimmune)
Summary
Description:
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Also Known As:
Thrombocytopenic Purpura, Autoimmune; Purpura, Thrombocytopenic, Idiopathic; Autoimmune Thrombocytopenia; Werlhof Disease; Autoimmune Thrombocytopenias Show All >>
Networked: 3202
relevant articles (178 outcomes,
236 trials/studies)
for this Disease
Key Drugs and Agents for Idiopathic Thrombocytopenic Purpura
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
-
Inosine Triphosphate (ITP)
:
90 outcomes 149 studies in 1697 results
: IBA
-
Intravenous Immunoglobulins (IVIG)
:
13 outcomes 13 studies in 112 results
:
FDA 1
-
Immunoglobulins (Immunoglobulin)
:
12 outcomes 16 studies in 198 results
: IBA
-
rituximab (Mabthera)
:
11 outcomes 7 studies in 90 results
:
FDA 3
-
Danazol (Azol)
:
8 outcomes 1 study in 49 results
:
FDA 5
Generic
-
Immunoglobulin G (IgG)
:
7 outcomes 8 studies in 196 results
: IBA
-
Dexamethasone (Maxidex)
:
5 outcomes 6 studies in 35 results
:
FDA 77
Generic
-
eltrombopag
:
5 outcomes 3 studies in 33 results
:
FDA 1
-
Prednisone (Sone)
:
5 outcomes 2 studies in 38 results
:
FDA 119
Generic
-
Prednisolone (Predate)
:
5 outcomes in 38 results
:
FDA 55
Generic
Show All >>
Diseases Related to Idiopathic Thrombocytopenic Purpura
-
Thrombocytopenia (Thrombopenia)
-
Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
-
Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
-
Systemic Lupus Erythematosus (Libman-Sacks Disease)
-
Hemolytic Anemia
Show All >>
Key Therapies for Idiopathic Thrombocytopenic Purpura
Efficacy Chart >>
-
Splenectomy
:
30 outcomes 28 studies in 470 results
-
Drug Therapy (Chemotherapy)
:
3 outcomes 1 study in 28 results
-
Transplants (Transplant)
:
2 outcomes 2 studies in 23 results
-
Platelet Transfusion (Blood Platelet Transfusions)
:
1 outcome 3 studies in 26 results
-
Aftercare (After-Treatment)
:
1 outcome 1 study in 13 results
Show All >>
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