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Severe Combined Immunodeficiency
(Bare Lymphocyte Syndrome)
Summary
Description:
Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).
Also Known As:
Bare Lymphocyte Syndrome; Immunodeficiency Syndrome, Severe Combined; Immunologic Deficiency, Severe Combined; Omenn's Syndrome; Reticuloendotheliosis, Familial Show All >>
Networked: 2083
relevant articles (58 outcomes,
157 trials/studies)
for this Disease
Key Drugs and Agents for Severe Combined Immunodeficiency
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
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Adenosine Deaminase
:
6 outcomes 21 studies in 223 results
: IBA
-
Antibodies
:
4 outcomes 3 studies in 29 results
: IBA
-
matrigel
:
2 outcomes 1 study in 8 results
: IBA
-
Immunotoxins (Immunotoxin)
:
2 outcomes in 8 results
: IBA
-
LBH589
:
2 outcomes in 2 results
: IBA
-
Severe combined immunodeficiency due to adenosine deaminase deficiency
:
1 outcome 3 studies in 73 results
: IBA
-
Immunoglobulin G (IgG)
:
1 outcome 3 studies in 36 results
: IBA
-
Complementary DNA (cDNA)
:
1 outcome 2 studies in 11 results
: IBA
-
Immunoglobulins (Immunoglobulin)
:
1 outcome 1 study in 28 results
: IBA
-
Streptozocin (Streptozotocin)
:
1 outcome 1 study in 17 results
:
FDA 1
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Diseases Related to Severe Combined Immunodeficiency
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Infection
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Neoplasms (Cancer)
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Leukemia
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Melanoma (Melanoma, Malignant)
-
Wiskott-Aldrich Syndrome (Syndrome, Wiskott-Aldrich)
Show All >>
Key Therapies for Severe Combined Immunodeficiency
Efficacy Chart >>
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Hematopoietic Stem Cell Transplantation
:
4 outcomes in 45 results
-
Transplantation (Transplant Recipients)
:
3 outcomes 8 studies in 184 results
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Bone Marrow Transplantation (Transplantation, Bone Marrow)
:
3 outcomes 2 studies in 151 results
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Drug Therapy (Chemotherapy)
:
2 outcomes 2 studies in 19 results
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Injections
:
2 outcomes 1 study in 12 results
Show All >>
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