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Radioimmunotherapy Summary

Description: Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).

Also Known As: Immunoradiotherapy; Immunoradiotherapies; Radioimmunotherapies

Networked: 1663 relevant articles (246 outcomes, 293 trials/studies) for this Therapy

Key Diseases for which Radioimmunotherapy is Relevant

  1. Neoplasms (Cancer) : 96 outcomes 98 studies in 721 results
  2. Non-Hodgkin Lymphoma (Lymphosarcoma) : 34 outcomes 40 studies in 291 results
  3. Lymphoma (Lymphomas) : 33 outcomes 17 studies in 166 results
  4. Ovarian Neoplasms (Ovarian Cancer) : 16 outcomes 16 studies in 61 results
  5. B-Cell Lymphoma (Lymphoma, B Cell) : 15 outcomes 16 studies in 77 results
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Drugs Related to Radioimmunotherapy

  1. Antibodies
  2. Monoclonal Antibodies
  3. ibritumomab tiuxetan (Zevalin)
  4. Carcinoembryonic Antigen
  5. Antigens
  6. rituximab (Mabthera)
  7. Immunoglobulin G (IgG)
  8. Paclitaxel (Taxol)
  9. Radioisotopes (Radionuclides)
  10. Immunoconjugates (Immunoconjugate)
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Therapies Related to Radioimmunotherapy

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Immunotherapy
  4. Transplants (Transplant)
  5. Radiotherapy
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