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Ocular Onchocerciasis (River Blindness) Summary

Description: Filarial infection of the eyes transmitted from person to person by bites of Onchocerca volvulus-infected black flies. The microfilariae of Onchocerca are thus deposited beneath the skin. They migrate through various tissues including the eye. Those persons infected have impaired vision and up to 20% are blind. The incidence of eye lesions has been reported to be as high as 30% in Central America and parts of Africa.

Also Known As: River Blindness; Onchocerciasis, Ocular; Blindness, River; Ocular Onchocerciases; Onchocerciases, Ocular

Networked: 104 relevant articles (7 outcomes, 12 trials/studies) for this Disease

Key Drugs and Agents for Ocular Onchocerciasis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Ivermectin (Mectizan) : 5 outcomes 3 studies in 42 results : FDA 1
  2. Diethylcarbamazine (Hetrazan) : 1 outcome 1 study in 7 results : FDA 1
  3. Doxycycline (Vibramycin) : 1 outcome 1 study in 3 results : FDA 23 Generic
  4. Ophthalmic Solutions (Eye Drops) : 1 outcome in 1 result : IBA
  5. Coffee : 1 outcome in 1 result : FDA 1
  6. Antigens : 3 studies in 15 results : IBA
  7. Suramin (Suramin Sodium) : 1 study in 3 results : IBA
  8. Cytokines : 1 study in 2 results : IBA
  9. Apolipoproteins C (ApoC) : 1 study in 2 results : IBA
  10. Interleukin-13 : 1 study in 1 result : IBA
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Diseases Related to Ocular Onchocerciasis

  1. Onchocerciasis
  2. Infection
  3. Body Weight (Weight, Body)
  4. Keratitis
  5. Inflammation
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Key Therapies for Ocular Onchocerciasis

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 5 results
  2. Intravitreal Injections : 1 result

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