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Calcitonin Gene-Related Peptide Summary

Description: Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.

Also Known As: Calcitonin Gene-Related Peptide I; Calcitonin Gene-Related Peptide II; alpha-CGRP; beta-CGRP; Calcitonin Gene Related Peptide Show All >>

Networked: 1883 relevant articles (44 outcomes, 233 trials/studies) for this Bio-Agent

Key Diseases for which Calcitonin Gene-Related Peptide is Relevant

  1. Migraine Disorders (Migraine) : 15 outcomes 36 studies in 311 results
  2. Headache (Headaches) : 3 outcomes 10 studies in 69 results
  3. Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) : 3 outcomes 2 studies in 24 results
  4. Heart Failure : 2 outcomes 9 studies in 20 results
  5. Ischemia : 2 outcomes 6 studies in 35 results
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Drugs Related to Calcitonin Gene-Related Peptide

  1. Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)
  2. Substance P
  3. N- (6- (2,3- difluorophenyl)- 2- oxo- 1- (2,2,2- trifluoroethyl)azepan- 3- yl)- 4- (2- oxo- 2,3- dihydro- 1H- imidazo(4,5- b)pyridin- 1- yl)piperidine- 1- carboxamide
  4. Neuropeptides
  5. Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
  6. calcitonin gene-related peptide (8-37)
  7. Vasodilator Agents (Vasodilators)
  8. olcegepant
  9. Neuropeptide Y
  10. Capsaicin (Zostrix)
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Therapies Related to Calcitonin Gene-Related Peptide

  1. Denervation
  2. Radiotherapy
  3. Aftercare (After-Treatment)
  4. Anesthesia
  5. Axotomy
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