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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP)
Summary
Description:
A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
Also Known As:
MPTP; N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl-
Networked: 2576
relevant articles (118 outcomes,
385 trials/studies)
for this Bio-Agent
Key Diseases for which 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is
Relevant
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Parkinson Disease (Parkinson's Disease)
:
52 outcomes 197 studies in 1272 results
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Parkinsonian Disorders (Parkinsonism)
:
14 outcomes 72 studies in 642 results
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Dyskinesias (Dyskinesia)
:
10 outcomes 39 studies in 204 results
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Ischemia
:
8 outcomes 10 studies in 99 results
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Reperfusion Injury
:
5 outcomes 10 studies in 81 results
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Drugs Related to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
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1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
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Dopamine (Intropin)
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Levodopa (L Dopa)
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1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)
-
mitochondrial permeability transition pore
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Neurotoxins
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Selegiline (E250)
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Monoamine Oxidase (MAO)
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Caffeine (No Doz)
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pioglitazone (Actos)
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Therapies Related to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
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Aftercare (After-Treatment)
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Injections
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Transplantation (Transplant Recipients)
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Denervation
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Acupuncture Points (Acupuncture Point)
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