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AIDS Dementia Complex Summary

Description: A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Also Known As: AIDS-Related Dementia Complex; Acquired-Immune Deficiency Syndrome Dementia Complex; Dementia Complex, Acquired Immune Deficiency Syndrome; Encephalopathy, AIDS; Encephalopathy, HIV Show All >>

Networked: 387 relevant articles (25 outcomes, 36 trials/studies) for this Disease

Key Drugs and Agents for AIDS Dementia Complex

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Zidovudine (Retrovir) : 6 outcomes 3 studies in 32 results : FDA 42 Generic
  2. Anti-Retroviral Agents (Antiretroviral Agents) : 2 outcomes in 4 results : IBA
  3. abacavir (Ziagen) : 1 outcome 3 studies in 4 results : FDA 17
  4. RNA (Ribonucleic Acid) : 1 outcome 2 studies in 14 results : IBA
  5. Protons (Proton) : 1 outcome 2 studies in 11 results : IBA
  6. N-acetylaspartate (N-acetyl aspartate) : 1 outcome 1 study in 8 results : IBA
  7. N-Methylaspartate (NMDA) : 1 outcome 1 study in 7 results : IBA
  8. Didanosine (Videx) : 1 outcome 1 study in 7 results : FDA 9 Generic
  9. Creatine : 1 outcome 1 study in 4 results : IBA
  10. Methylphenidate (Ritalin) : 1 outcome 1 study in 1 result : FDA 25 Generic
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Diseases Related to AIDS Dementia Complex

  1. Acquired Immunodeficiency Syndrome (AIDS)
  2. Infection
  3. Parkinson Disease (Parkinson's Disease)
  4. Opportunistic Infections (Opportunistic Infection)
  5. Dementia (Dementias)
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Key Therapies for AIDS Dementia Complex

Efficacy Chart >>
  1. Highly Active Antiretroviral Therapy (HAART) : 8 outcomes 7 studies in 46 results
  2. First Aid (Aids, First) : 1 study in 2 results
  3. Drug Therapy (Chemotherapy) : 3 results
  4. Art Therapy : 3 results
  5. Aftercare (After-Treatment) : 3 results
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