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B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) Summary

Description: A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.

Also Known As: Chronic Lymphocytic Leukemia; Lymphoma, Small Cell; Leukemia, B Cell, Chronic; Leukemia, Chronic Lymphoblastic; Leukemia, Chronic Lymphocytic Show All >>

Networked: 5913 relevant articles (343 outcomes, 653 trials/studies) for this Disease

Key Drugs and Agents for B-Cell Chronic Lymphocytic Leukemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. fludarabine : 91 outcomes 100 studies in 596 results : IBA
  2. rituximab (Mabthera) : 66 outcomes 70 studies in 402 results : FDA 3
  3. alemtuzumab (Campath) : 34 outcomes 36 studies in 238 results : FDA 2
  4. Cyclophosphamide (Cytoxan) : 31 outcomes 46 studies in 200 results : FDA 10 Generic
  5. Chlorambucil (Leukeran) : 22 outcomes 35 studies in 176 results : FDA 1
  6. Cladribine : 22 outcomes 33 studies in 139 results : FDA 3 Generic
  7. purine : 16 outcomes 11 studies in 121 results : IBA
  8. bendamustine : 9 outcomes 15 studies in 91 results : FDA 2
  9. Monoclonal Antibodies : 9 outcomes 8 studies in 132 results : IBA
  10. lenalidomide (CC 5013) : 8 outcomes 12 studies in 64 results : FDA 2
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Diseases Related to B-Cell Chronic Lymphocytic Leukemia

  1. Non-Hodgkin Lymphoma (Lymphosarcoma)
  2. Neoplasms (Cancer)
  3. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
  4. Hairy Cell Leukemia
  5. Lymphoma (Lymphomas)
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Key Therapies for B-Cell Chronic Lymphocytic Leukemia

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 26 outcomes 33 studies in 278 results
  2. Immunotherapy : 11 outcomes 6 studies in 60 results
  3. Transplants (Transplant) : 10 outcomes 7 studies in 84 results
  4. Stem Cell Transplantation : 9 outcomes 13 studies in 86 results
  5. Combination Drug Therapy (Combination Chemotherapy) : 7 outcomes 1 study in 30 results
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